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Merck

T6442

Anti-TRPC6 antibody produced in rabbit

affinity isolated antibody, lyophilized powder

Synonym(s):

Anti-Transient receptor potential cation channel, subfamily C, member 6 antibody produced in rabbit

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0.2 ML

€ 954,00

€ 954,00


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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:

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Product Name

Anti-TRPC6 antibody produced in rabbit, affinity isolated antibody, lyophilized powder

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

mouse, rat

technique(s)

immunohistochemistry: suitable using mouse brain sections
western blot: 1:200-1:400 using rat brain or lung lysates

UniProt accession no.

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

Gene Information

human ... TRPC6(7225)
mouse ... Trpc6(22068)
rat ... Trpc6(89823)

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This Item
T5067T0325SAB2102583
biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

rabbit

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

100

UniProt accession no.

Q61143

UniProt accession no.

Q9JMI9

UniProt accession no.

-

UniProt accession no.

Q9Y210

species reactivity

mouse, rat

species reactivity

rat

species reactivity

rat

species reactivity

human, pig

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

synthetic peptide (RRNESQDYLLMDELG) corresponding to amino acids residues 24-38 of mouse TRPC6. This sequence is identical in rat and highly homologous (15/16 residues identical) in human.

Physical form

Lyophilized from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin, and 0.05% sodium azide.

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Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


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Chengkang He et al.
JCI insight, 7(5) (2022-01-26)
Currently, the most effective strategy for dealing with Alzheimer's disease (AD) is delaying the onset of dementia. Severe hypoglycemia is strongly associated with dementia; however, the effects of recurrent moderate hypoglycemia (RH) on the progression of cognitive deficits in patients
Yonghong Bai et al.
eLife, 9 (2020-03-10)
Transient receptor potential canonical (TRPC) proteins form nonselective cation channels that play physiological roles in a wide variety of cells. Despite growing evidence supporting the therapeutic potential of TRPC6 inhibition in treating pathological cardiac and renal conditions, mechanistic understanding of
Yanna Du et al.
Molecular medicine reports, 16(2), 1117-1124 (2017-06-20)
Persistent pulmonary hypertension of the newborn (PPHN) is a life‑threatening disease that is commonly observed in the neonatal intensive care unit. PPHN is pathologically characterized by pulmonary vascular remodeling and, in particular, pulmonary artery smooth muscle cell (PASMC) proliferation. Decreased
Ying Meng et al.
International journal of molecular medicine, 37(1), 258-266 (2016-01-01)
Ischemia-reperfusion (I/R) plays an important role in myocardial injury. In the present study, we aimed to examine the protective effects of Danshensu (DSS) against I/R injury and to elucidate the underlying mechanisms. For this purpose, H9c2 cells were cultured in hypoxic solution
M Salomonsson et al.
Acta physiologica (Oxford, England), 200(3), 265-278 (2010-04-30)
In rat afferent arterioles we investigated the role of Na(+) entry in noradrenaline (NA)-induced depolarization and voltage-dependent Ca(2+) entry together with the importance of the transient receptor potential channel (TRPC) subfamily for non-voltage-dependent Ca(2+) entry. R (340/380) Fura-2 fluorescence was

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