T8877 is tested for solubility at 50 mg/ml in water. Although no suitability testing is performed, 2,3,5-Triphenyltetrazolium chloride (Tetrazolium Red) is often used to assess plant viability using a 10 mg/ml solution. Other uses, such as staining brain or heart tissue, have been reported.
T8877
2,3,5-Triphenyltetrazolium chloride
≥98.0% (HPLC)
2,3,5-Triphenyltetrazolium chloride
1 of 2 reviewers received a sample product or took part in a promotion
Synonym(s):
TPTZ, TTZ, Tetrazolium Red
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5 G
€ 53,50
10 G
€ 92,20
25 G
€ 175,00
50 G
€ 296,00
100 G
€ 523,00
About This Item
Empirical Formula (Hill Notation):
C19H15ClN4
CAS Number:
Molecular Weight:
334.80
Beilstein:
3923356
EC Number:
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47
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Assay
≥98.0% (HPLC)
form
powder
color
faintly yellow
solubility
H2O: 50 mg/mL
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
2-8°C
SMILES string
[Cl-].c1ccc(cc1)-c2nn(-c3ccccc3)[n+](n2)-c4ccccc4
InChI
1S/C19H15N4.ClH/c1-4-10-16(11-5-1)19-20-22(17-12-6-2-7-13-17)23(21-19)18-14-8-3-9-15-18;/h1-15H;1H/q+1;/p-1
InChI key
PKDBCJSWQUOKDO-UHFFFAOYSA-M
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This Item | 294438 | S4131 | N7005 |
|---|---|---|---|
| form powder | form powder | form powder | form powder |
| application(s) diagnostic assay manufacturing | application(s) diagnostic assay manufacturing | application(s) diagnostic assay manufacturing | application(s) diagnostic assay manufacturing |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. room temp | storage temp. 2-8°C |
| solubility H2O: 50 mg/mL | solubility acetonitrile: 50 mg/mL | solubility chloroform: 1 mg/mL, clear, red | solubility water: 10 mg/mL, dark red |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
| assay ≥98.0% (HPLC) | assay 97% | assay - | assay - |
General description
2,3,5-Triphenyltetrazolium chloride is a colorless water-soluble dye. In the mitochondria of living cells, it is reduced to a deep red, water-insoluble compound (formazan). 2,3,5-Triphenyltetrazolium chloride helps to distinguish between viable and infarcted brain tissue after stroke.[1]
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Product No.
Description
Pricing
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Flam. Sol. 1 - Skin Irrit. 2
Storage Class Code
4.1B - Flammable solid hazardous materials
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Mannitol-facilitated perfusion staining with 2,3,5-triphenyltetrazolium chloride (TTC) for detection of experimental cerebral infarction and biochemical analysis.
Sun YY et al.
Journal of Neuroscience Methods, 203, 122-122 (2012)
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Over the past 30 years a number of animal models of cerebral ischemic injury have been developed. Middle cerebral artery occlusion (MCAO) in particular reproduces both ischemic and reperfusion elements and is widely utilized as a model of ischemic stroke in
Human umbilical mesenchymal stem cells promote recovery after ischemic stroke.
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Cardiomyocyte apoptosis is a major cause of myocardial ischemia/reperfusion (MI/R) injury, in which the activation of the signal transducer and activator of transcription 1 (STAT1) plays an important role. The E3-ubiquitin ligase TRIM6 has been implicated in regulating STAT1 activity
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Hello, I wasn’t able to find the recommended proportion of product to water. Could you let me know what ratio I should use? Also, should I be using distilled water? Thank you!
1 answer-
Helpful?
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Bonjour, après avoir reconstitué la poudre dans de l'eau stérile, combien de temps pouvons-nous conserver la préparation au réfrigérateur ? Merci
1 answer-
The long-term solution stability of this product has not been determined. However, product 17779, a sterile 1% solution, has a shelf life of approximately 3 years. Provided that the solution is filter sterilized and stored properly at 2-8°C, a similar shelf life would be expected. Please see the link below to review this product:
https://www.sigmaaldrich.com/product/sial/17779Helpful?
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