USP

Tranexamic acid

Name: Tranexamic acid
Brand: USP
Price: 440 EUR

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

trans-4-(Aminomethyl)cyclohexanecarboxylic acid, AMCA, AMCHA, HAKU, TAMCHA, Tranexamic acid

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200 MG

€ 440,00

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About This Item

Linear Formula:

H₂NCH₂C₆H₁₀CO₂H

CAS Number:

1197-18-8

Molecular Weight:

157.21

Beilstein:

2207452

MDL number:

MFCD00001466

UNSPSC Code:

41116107

PubChem Substance ID:

329751362

NACRES:

NA.24

Key Documents

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grade

pharmaceutical primary standard

API family

tranexamic acid

manufacturer/tradename

USP

mp

>300 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

NC[C@H]1CC[C@@H](CC1)C(O)=O

InChI

1S/C8H15NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h6-7H,1-5,9H2,(H,10,11)/t6-,7-

InChI key

GYDJEQRTZSCIOI-LJGSYFOKSA-N

Gene Information

human ... PLG(5340)

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Show Differences

1 of 4

This Item	T1810000	BP734	PHR1812
USP 1672745 Tranexamic acid	T1810000 Tranexamic acid	BP734 Tranexamic acid impurity standard	Supelco PHR1812 Tranexamic acid
manufacturer/tradename USP	manufacturer/tradename EDQM	manufacturer/tradename BP	manufacturer/tradename -
grade pharmaceutical primary standard	grade pharmaceutical primary standard	grade pharmaceutical primary standard	grade certified reference material, pharmaceutical secondary standard
format neat	format neat	format mixture	format neat
application(s) pharmaceutical (small molecule)	application(s) pharmaceutical (small molecule)	application(s) pharmaceutical pharmaceutical small molecule	application(s) pharmaceutical (small molecule)
API family tranexamic acid	API family tranexamic acid	API family tranexamic acid	API family tranexamic acid
mp >300 °C (lit.)	mp >300 °C (lit.)	mp >300 °C (lit.)	mp >300 °C (lit.)

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Tranexamic acid USP Reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

Tranexamic Acid Tablets
Tranexamic Acid Injection

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Other Notes

Sales restrictions may apply.

Pictograms

GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Precautionary Statements

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

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Systematic review and meta-analysis of the use of tranexamic acid in tonsillectomy.

Chee Ching Chan et al.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 270(2), 735-748 (2012-09-22)

Post-tonsillectomy haemorrhage is a serious complication that can lead to death despite the fact that tonsillectomy is one of the commonest procedures performed in otolaryngology. Post-operative haemorrhage can be reduced by a potent antifibrinolytic agent such as tranexamic acid (TXA).

A prospective study on role of tranexamic acid in reducing postoperative blood loss in total knee arthroplasty and its effect on coagulation profile.

Anshul Dahuja et al.

The Journal of arthroplasty, 29(4), 733-735 (2013-11-05)

Total knee arthroplasty(TKA) is associated with extensive postoperative blood loss. Despite various studies proving the efficacy of Tranexamic Acid (TEA) with single or multiple boluses of different sizes with or without subsequent infusions, no consensus has been reached on the

Topical administration of tranexamic acid in primary total hip and total knee arthroplasty.

Joseph G Martin et al.

The Journal of arthroplasty, 29(5), 889-894 (2013-11-19)

Major blood loss is a known potential complication in total hip and total knee arthroplasty. We conducted a prospective, stratified, randomized, double-blind, placebo-controlled trial that evaluated 100 patients undergoing total knee or total hip arthroplasty to evaluate the effect on

Tranexamic acid in trauma: how should we use it?

Lena M Napolitano et al.

The journal of trauma and acute care surgery, 74(6), 1575-1586 (2013-05-23)

In-hospital C-reactive protein predicts outcome after aneurysmal subarachnoid haemorrhage treated by endovascular coiling.

L Z Csajbok et al.

Acta anaesthesiologica Scandinavica, 59(2), 255-264 (2015-01-20)

This study aimed to examine prospectively whether the inflammatory marker C-reactive protein (CRP) increases in patients with aneurysmal subarachnoid haemorrhage (aSAH) treated by endovascular coiling and investigate whether CRP could be used as prognostic factor for long-term neurological outcome. This

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