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Biological applications of gold nanoparticles.

Journal of nanoscience and nanotechnology (2014-04-16)
Monic Shah, Vivek D Badwaik, Rajalingam Dakshinamurthy
ABSTRACT

This article reviews some of the recent biological applications of gold nanoparticles (GNPs) which have been discovered lately by individual studies all around the world. GNPs have emerged as a promising candidates for various biological applications due to their unique physical properties (size and shape dependent), excellent biocompatibility, facile synthesis, ease of bioconjugation, etc. This review starts with a brief introduction about nanotechnology followed by an insight into the history, emergence, and enhanced properties of various gold nanostructures, which form the basis for their numerous biomedical applications. In addition, a brief overview on some of the commonly used fabrication techniques for synthesizing GNPs is also discussed. Finally, a miscellany of the latest biological applications of GNPs, such as cancer diagnostics and therapy, biological probes, drug delivery, gene delivery, vaccine preparation, brain implants, artificial skin, sterilization system, and improving electrical signaling in the heart, published in different articles in reputed journals are highlighted.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Gold, powder, <850 μm, ≥99.99% trace metals basis
Sigma-Aldrich
Gold, foil, thickness 0.025 mm, 99.99% trace metals basis
Sigma-Aldrich
Gold, evaporation slug, diam. × L 0.3 cm × 0.6 cm, 99.99% trace metals basis
Sigma-Aldrich
Gold, foil, thickness 0.127 mm, 99.99% trace metals basis
Sigma-Aldrich
Gold, wire, diam. 0.5 mm, 99.999% trace metals basis
Sigma-Aldrich
Gold, wire, diam. 1.0 mm, 99.99% trace metals basis
Sigma-Aldrich
Gold coated glass slide, layer thickness 1000 Å, 99.999% (Au)
Sigma-Aldrich
Gold, wire, diam. 0.25 mm, 99.99% trace metals basis
Sigma-Aldrich
Gold, foil, thickness 0.1 mm, 99.99% trace metals basis
Sigma-Aldrich
Gold coated glass cover slip, 99.999% (Au), diam. × thickness 15 mm × 130-170 μm, layer thickness 100 Å
Sigma-Aldrich
Gold coated glass slide, layer thickness 100 Å, 99.999% (Au)
Gold, insulated wire, 2m, conductor diameter 0.125mm, insulation thickness 0.016mm, PTFE (polytetrafluoroethylene) insulation, 99.99%
Gold, insulated wire, 0.5m, conductor diameter 0.05mm, insulation thickness 0.009mm, PTFE (polytetrafluoroethylene) insulation, 99.99%
Gold, tube, 50mm, outside diameter 2.0mm, inside diameter 1.8mm, wall thickness 0.1mm, as drawn, 99.95%
Gold, insulated wire, 5m, conductor diameter 0.025mm, insulation thickness 0.005mm, polyester insulation, 99.99%
Gold, microfoil, disks, 10mm, thinness 0.75μm, specific density 1449μg/cm2, permanent mylar 3.5μm support, 99.99+%
Gold, insulated wire, 1m, conductor diameter 0.125mm, insulation thickness 0.016mm, PTFE (polytetrafluoroethylene) insulation, 99.99%
Gold, tube, 100mm, outside diameter 8mm, inside diameter 7.8mm, wall thickness 0.1mm, as drawn, 99.95%
Gold, insulated wire, 1m, conductor diameter 0.125mm, insulation thickness 0.014mm, polyester insulation, 99.99%
Gold, microfoil, disks, 10mm, thinness 1.0μm, specific density 1932μg/cm2, permanent mylar 3.5μm support, 99.99+%
Gold, rod, 25mm, diameter 1.6mm, as drawn, 99.95%
Gold, insulated wire, 2m, conductor diameter 0.025mm, insulation thickness 0.005mm, polyester insulation, 99.99%
Gold, insulated wire, 0.2m, conductor diameter 0.125mm, insulation thickness 0.016mm, PTFE (polytetrafluoroethylene) insulation, 99.99%
Gold, microleaf disks, 10mm, thinness 1.0μm, specific density 1932μg/cm2, removable support, 99.99+%
Gold, insulated wire, 5m, conductor diameter 0.05mm, insulation thickness 0.007mm, polyimide insulation, 99.99%
Gold, tube, 10mm, outside diameter 0.15mm, inside diameter 0.05mm, wall thickness 0.05mm, as drawn, 99.95%
Gold, tube, 50mm, outside diameter 0.3mm, inside diameter 0.2mm, wall thickness 0.05mm, as drawn, 99.95%
Gold, sphere, 20pcs, diameter 0.5mm, 99.99%
Gold, insulated wire, 1m, conductor diameter 0.025mm, insulation thickness 0.005mm, polyester insulation, 99.99%
Gold, microleaf disks, 10mm, thinness 0.25μm, specific density 483μg/cm2, removable support, 99.99+%