SIRT1
sirtuin 1
Synonymes:
SIR2L1
Espèce(s):
Human SIRT1 (23411), Mouse Sirt1 (93759), Rat Sirt1 (309757), cow SIRT1 (613629), naked mole-rat Sirt1 (101720282), dog SIRT1 (489012), domestic cat SIRT1 (101087610), chicken SIRT1 (423646), Zebrafish sirt1 (797132), domestic guinea pig Sirt1 (100717014) ...Plus
ID UniProtKB:
ID du gène:
- Human(23411) Summary: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]
- Mouse(93759) sirtuin 1
- Rat(309757) sirtuin 1
- cow(613629) sirtuin 1
- naked mole-rat(101720282) sirtuin 1
- dog(489012) sirtuin 1
- domestic cat(101087610) sirtuin 1
- chicken(423646) sirtuin 1
- Zebrafish(797132) sirtuin (silent mating type information regulation 2 homolog) 1
- domestic guinea pig(100717014) sirtuin 1
- sheep(101102956) sirtuin 1
- Domestic Rabbit(100349271) sirtuin 1
- Horse(100072571) sirtuin 1
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ELISA
Numéro du produit
Description
Espèce(s)
Small Molecule - Activator
Numéro du produit
Description
Espèce(s)
Activity Assay
Numéro du produit
Description
Espèce(s)
Antibodies
Numéro du produit
Description
Espèces réactives
Application
Anti Sirtuin 1 Antibody, clone 23GB1610, Rabbit Monoclonal, clone 23GB1610, recombinant rabbit monoclonal, expressed in HEK293 cells,
Espèces réactives
human
Application
flow cytometry
immunofluorescence
western blot
immunofluorescence
western blot
Anti-phospho-SIRT1 (Ser47) Antibody, clone 23GB1540, Rabbit Monoclonal, clone 23GB1540, recombinant rabbit monoclonal, expressed in HEK293 cells,
Espèces réactives
human
Application
flow cytometry
immunofluorescence
western blot
immunofluorescence
western blot
Anti-SIRT1 Antibody, clone 10E4, clone 10-E-4, from mouse,
Espèces réactives
human, mouse
Application
ChIP
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-SIRT1 antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-Sirt1 antibody, Mouse monoclonal, clone SIR11, purified from hybridoma cell culture,
Espèces réactives
mouse
Application
ELISA
microarray
western blot
microarray
western blot
Small Molecule - Inhibitor
Proteins
Numéro du produit
Description
Espèce(s)
Sirt1 human, recombinant, expressed in E. coli, N-terminal histidine tagged, ≥90% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human
SIRT1, active, His tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human