D3689

(S)-3,5-Dihydroxyphenylglycine hydrate

≥98% (HPLC), group I metabotropic glutamate receptor agonist, powder

• Synonyme(s) : S-DHPG
• Formule empirique (notation de Hill) : C₈H₉NO₄ · xH₂O
• Numéro CAS: 162870-29-3
• Poids moléculaire : 183.16 (anhydrous basis)
• UNSPSC Code: 12352209
• PubChem Substance ID: 24278366
• NACRES: NA.77
• MDL number: MFCD11044457

Propriétés

• Nom du produit: (S)-3,5-Dihydroxyphenylglycine hydrate, ≥98% (HPLC), powder
• SMILES string: O.N[C@H](C(O)=O)c1cc(O)cc(O)c1
• InChI: 1S/C8H9NO4.H2O/c9-7(8(12)13)4-1-5(10)3-6(11)2-4;/h1-3,7,10-11H,9H2,(H,12,13);1H2/t7-;/m0./s1
• InChI key: QZEFIWWBQUKNFA-FJXQXJEOSA-N
• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated; protect from light
• color: white
• storage temp.: −20°C
• Quality Level: 100
• Gene Information: human ... GRM1(2911)

Description

Application

(S)-3,5-Dihydroxyphenylglycine hydrate has been used:

• as mGluR1/5 agonist for metabotropic glutamate receptor 1 (mGluR1/5) activation in synaptoneurosomal preparations
• in ACSF for DHPG stimulation
• to inject into basolateral amygdala to study its effect on memory expression

Biochem/physiol Actions

(S)-3,5-Dihydroxyphenylglycine hydrate is a group I metabotropic glutamate receptor agonist.

Disclaimer

air sensitive

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Informations sur la sécurité

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves