COX6A2
cytochrome c oxidase subunit VIa polypeptide 2
Synonyme:
COX6AH, COXVIAH
Spezies:
Human COX6A2 (1339), Mouse Cox6a2 (12862), Rat Cox6a2 (25278), Zebrafish cox6a2 (447942), cow COX6A2 (282200), dog COX6A2 (479780)
UniProtKB-ID:
Gen-ID:
- Human(1339) Summary: Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (heart/muscle isoform) of subunit VIa, and polypeptide 2 is present only in striated muscles. Polypeptide 1 (liver isoform) of subunit VIa is encoded by a different gene, and is found in all non-muscle tissues. These two polypeptides share 66% amino acid sequence identity. [provided by RefSeq, Jul 2008]
- Mouse(12862) cytochrome c oxidase subunit VIa polypeptide 2
- Rat(25278) cytochrome c oxidase subunit VIa polypeptide 2
- Zebrafish(447942) cytochrome c oxidase subunit VIa polypeptide 2
- cow(282200) cytochrome c oxidase subunit VIa polypeptide 2
- dog(479780) cytochrome c oxidase subunit VIa polypeptide 2
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