AB5428P

Anti-Per2 Antibody

Name: Anti-Per2 Antibody
Brand: MM
Price: 529 CHF

Chemicon^®, from rabbit

Synonym(s):

Period Circadian Protein 2

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50 μG

CHF 529.00

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About This Item

UNSPSC Code:

12352203

eCl@ss:

32160702

NACRES:

NA.41

Key Documents

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biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

mouse

manufacturer/tradename

Chemicon^®

technique(s)

ELISA: suitable
western blot: suitable

NCBI accession no.

NM_003894.3
NM_022817.2

UniProt accession no.

O15055

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

mouse ... Per2(18627)

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This Item	AB2202	ZRB1076	AB5424P
Sigma-Aldrich AB5428P Anti-Per2 Antibody	Sigma-Aldrich AB2202 Anti-PER2 Antibody	Sigma-Aldrich ZRB1076 Anti-PER2 Antibody, clone 1G17 ZooMAb^® Rabbit Monoclonal	Sigma-Aldrich AB5424P Anti-Per1 Antibody
Quality Level 100	Quality Level 100	Quality Level 200	Quality Level 100
biological source rabbit	biological source rabbit	biological source rabbit	biological source rabbit
antibody form affinity purified immunoglobulin	antibody form serum	antibody form purified antibody	antibody form affinity purified immunoglobulin
species reactivity mouse	species reactivity mouse, rat	species reactivity human	species reactivity rat, mouse, human
technique(s) ELISA: suitable, western blot: suitable	technique(s) western blot: suitable	technique(s) affinity binding assay: suitable, immunocytochemistry: suitable, immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable	technique(s) ELISA: suitable, western blot: suitable
shipped in dry ice	shipped in wet ice	shipped in ambient	shipped in dry ice

Immunogen

A 23 amino acid peptide sequence within the C-teriminus of mouse Per 2 (Albretch et al. 1997; Shearman et al. 1997; Sakamoto et al. 1998).

Application

Detect Per2 using this Anti-Per2 Antibody validated for use in ELISA & WB.

Research Category
Neuroscience

Research Sub Category
Circadian Rhythm & Sleep

Western blot: 1-10 μg/mL using ECL.

ELISA: 50-100 ng of control peptide per well.

Optimal working dilutions must be determined by the end user.

Biochem/physiol Actions

Recognizes mouse Per 2. The immunogen shows no significant sequence homology with Per 1 or Per 3.

SPECIES REACTIVITIES: The immunogen sequence has 77% homology with rat Per2. No significant homology is seen with human Per 2 (Nagase et al. 1997). Reactivity with other species has not been confirmed.

Physical form

Affinity purified immunoglobulin. Liquid in PBS containing 0.1% BSA and 0.05% sodium azide.

Preparation Note

Maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Reversible dysregulation of renal circadian rhythm in lupus nephritis.

Rakesh Mishra et al.

Molecular medicine (Cambridge, Mass.), 27(1), 99-99 (2021-09-08)

We have found disruption of expression of major transcriptional regulators of circadian rhythm in the kidneys of several mouse models of lupus nephritis. Here we define the consequence of this disturbance with respect to circadian gene expression and renal homeostatic

Cysteine Oxidation Promotes Dimerization/Oligomerization of Circadian Protein Period 2.

Fernando Martin Baidanoff et al.

Biomolecules, 12(7) (2022-07-28)

The molecular circadian clock is based on a transcriptional/translational feedback loop in which the stability and half-life of circadian proteins is of importance. Cysteine residues of proteins are subject to several redox reactions leading to S-thiolation and disulfide bond formation

The Circadian Clock Gene BMAL1 Coordinates Intestinal Regeneration.

Kyle Stokes et al.

Cellular and molecular gastroenterology and hepatology, 4(1), 95-114 (2017-06-09)

The gastrointestinal syndrome is an illness of the intestine caused by high levels of radiation. It is characterized by extensive loss of epithelial tissue integrity, which initiates a regenerative response by intestinal stem and precursor cells. The intestine has 24-hour

Heterogeneous expression of the core circadian clock proteins among neuronal cell types in mouse retina.

Xiaoqin Liu et al.

PloS one, 7(11), e50602-e50602 (2012-11-29)

Circadian rhythms in metabolism, physiology, and behavior originate from cell-autonomous circadian clocks located in many organs and structures throughout the body and that share a common molecular mechanism based on the clock genes and their protein products. In the mammalian

The day/night proteome in the murine heart.

Peter Podobed et al.

American journal of physiology. Regulatory, integrative and comparative physiology, 307(2), R121-R137 (2014-05-03)

Circadian rhythms are essential to cardiovascular health and disease. Temporal coordination of cardiac structure and function has focused primarily at the physiological and gene expression levels, but these analyses are invariably incomplete, not the least because proteins underlie many biological

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