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Merck

CDK7

cyclin-dependent kinase 7

Sinonimi:
CAK1, CDKN7, HCAK, MO15, STK1, p39MO15
Specie:
Human CDK7 (1022), Mouse Cdk7 (12572), Rat Cdk7 (171150), domestic guinea pig Cdk7 (100725955), naked mole-rat Cdk7 (101702664), sheep CDK7 (101119934), Horse CDK7 (100049964), Zebrafish cdk7 (405897), dog CDK7 (608441), domestic cat CDK7 (101086781) ...Più
ID UniProtKB:
P50613, Q9BS60, Q9UE19
ID gene:
  • Human(1022) Summary: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle. [provided by RefSeq, Jul 2008]
  • Mouse(12572) cyclin-dependent kinase 7
  • Rat(171150) cyclin-dependent kinase 7
  • domestic guinea pig(100725955) cyclin-dependent kinase 7
  • naked mole-rat(101702664) cyclin-dependent kinase 7
  • sheep(101119934) cyclin-dependent kinase 7
  • Horse(100049964) cyclin-dependent kinase 7
  • Zebrafish(405897) cyclin-dependent kinase 7
  • dog(608441) cyclin-dependent kinase 7
  • domestic cat(101086781) cyclin-dependent kinase 7
  • chicken(771294) cyclin-dependent kinase 7
  • cow(515462) cyclin-dependent kinase 7
  • fruit fly(31441) Cyclin-dependent kinase 7

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Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
HPA007932
Anti-CDK7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
western blot
ABE1317
Anti-phospho Cyclin-dependent kinase 7 (Thr170) Antibody, from rabbit, purified by affinity chromatography,
Reattività con
human, mouse, rat
Applicazione
ChIP
western blot
C7089
Monoclonal Anti-Cdk7/CAK antibody produced in mouse, clone MO-1.1, ascites fluid,
Reattività con
human
Applicazione
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
microarray
western blot
SAB4504143
Anti-phospho-CDK7 (pThr170) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunohistochemistry
western blot
HPA008453
Anti-CDK7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
western blot

Small Molecule - Inhibitor

Numero di prodotto
Descrizione
Specie
F3055
Flavopiridol, ≥98% (HPLC), powder,
Specie
human
R7772
Roscovitine, ≥98% (TLC),
Specie
human, mouse, rat
O0886
Olomoucine, ≥98% (HPLC),
Specie
human, rat

Proteins

Numero di prodotto
Descrizione
Specie
14-476-M
Cdk7/Cyclin H/MAT1 (CAK complex) Protein, active, 10 µg, Active complex of recombinant full length human Cdk7, containing a C-terminal His6-tag, recombinant full-length human Cyclin H untagged & recombinant full-length human MAT1 containing an N-terminal GST-tag, for use in Kinase Assays.,
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
EMU067531
MISSION® esiRNA, targeting mouse Cdk7,
Specie
mouse
EHU108561
MISSION® esiRNA, targeting human CDK7,
Specie
human

Small Molecule - Substrate

Numero di prodotto
Descrizione
Specie
12-526
Cdk7/9tide, ,
Specie
human