8.52014

Fmoc-Nle-OH

≥98.0% (HPLC), for peptide synthesis, Novabiochem^®

• Synonym(s): Fmoc-Nle-OH, N-α-Fmoc-L-norleucine
• Empirical Formula (Hill Notation): C₂₁H₂₃NO₄
• CAS Number: 77284-32-3
• Molecular Weight: 353.41
• UNSPSC Code: 12352209
• NACRES: NA.22
• MDL number: MFCD00037537
• eCl@ss: 32150313

Properties

• Product Name: Fmoc-Nle-OH, Novabiochem^®
• Quality Segment: 200
• product line: Novabiochem^®
• assay: ≥96.0% (acidimetric), ≥98% (TLC), ≥98.0% (HPLC)
• form: powder
• reaction suitability: reaction type: Fmoc solid-phase peptide synthesis
• manufacturer/tradename: Novabiochem^®
• mp: 135-145 °C
• application(s): peptide synthesis
• functional group: Fmoc
• storage temp.: 2-30°C
• SMILES string: N(=C(/[O-])\OCC1c2c(cccc2)c3c1cccc3)/[C@H](CCCC)C(=O)O
• InChI: 1S/C21H23NO4/c1-2-3-12-19(20(23)24)22-21(25)26-13-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,2-3,12-13H2,1H3,(H,22,25)(H,23,24)/p-1/t19-/m1/s1
• InChI key: VCFCFPNRQDANPN-LJQANCHMSA-M

Description

General description

Standard building block for introduction of norleucine amino-acid residues by Fmoc SPPS

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (25 mmole in 50 ml DMF): clearly soluble
UV/VIS (E(450 bis 600 nm)): ≤ 50 mAU
Assay (acidimetric): ≥ 96.0 %
Water (K. F.): ≤ 1.00 %

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Other Notes

Replaces: 04-12-1028

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable