200-05N

Human Umbilical Vein Endothelial Cells: HUVEC, neonatal

• Synonym(s): HUVEC cells
• NACRES: NA.81
• UNSPSC Code: 41106514
• Biological source: human umbilicus (normal veins)
• Growth mode: Adherent
• Morphology: Endothelial
• Relevant disease(s): arthritis; diabetes; cancer; cardiovascular diseases

Properties

• biological source: human umbilicus (normal veins)
• packaging: pkg of 500,000 cells
• manufacturer/tradename: Cell Applications, Inc
• growth mode: Adherent
• karyotype: 2n = 46
• morphology: Endothelial
• technique(s): cell culture | mammalian: suitable
• relevant disease(s): arthritis; diabetes; cancer; cardiovascular diseases
• shipped in: dry ice
• storage temp.: −196°C

Description

General description

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Human Umbilical Vein Endothelial Cells (HUVEC) provide a classic model system to study many aspects of endothelial function and disease, such as normal, abnormal and tumor-associated angiogenesis, oxidative stress, hypoxia and inflammation related pathways in endothelia under normal and pathological conditions, cardiovascular-related complications associated with various diseases, mode of action and cardiovascular protection effects of various compounds, etc.

Application

angiogenesis, cell signaling pathways, migration, invasion, growth factors, tube formation, vascular homeostasis, modulation of blood vessel tone, regulate cell grwoth and ECM deposition, vasculoregulation

Biochem/physiol Actions

Vein

Preparation Note

• Primary culture, >500,000 cells in Endothelial Cell Basal Medium containing 10% FBS & 10% DMSO
• Can be cultured at least 16 doublings

Please refer to the HUVEC Culture Protocol.

Other Notes

Endothelial Cell Basal Medium containing 10% FBS & 10% DMSO

Safety Information

• Storage Class: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable