45124

Elastase from porcine pancreas

powder, white, ≥10 U/mg

• Synonym(s): Elastase from hog pancreas, Pancreatopeptidase E
• CAS Number: 39445-21-1
• UNSPSC Code: 12352204
• NACRES: NA.54
• EC Number: 254-453-6
• MDL number: MFCD00130998
• EC Number: 3.4.21.36 (BRENDA, IUBMB)
• Specific activity: ≥10 U/mg
• Biological source: Porcine pancreas

Properties

• biological source: Porcine pancreas
• form: powder
• specific activity: ≥10 U/mg
• mol wt: M_r ~25000
• color: white
• storage temp.: −20°C

Description

Biochem/physiol Actions

Elastase hydrolyses elastin, the specific protein of elastic fibers, and digests hemoglobin, casein and fibrin.

Other Notes

Cleaves polyalanyl-lysine peptides at the alanyl-lysine bond, review; Review, elastase-type proteases

1 U corresponds to the amount of enzyme which liberates 1 μmol 4-nitroaniline per minute at 25°C and pH 7.8 (succinyl-(L-Ala)₃-4-nitroanilide as substrate)

One unit will hydrolyze 1.0 μmole of N-succinyl-L-Ala-Ala-Ala-p-nitroanilide per min, pH 8.0 at 25 °C.

Sales restrictions may apply

Safety Information

• Pictograms: GHS08,GHS07
• Signal Word: Danger
• Hazard Codes: H315,H319,H334,H335
• Precautionary Statements: P261 - P280 - P284 - P304 + P340 + P312 - P337 + P313 - P342 + P311
• Hazard Classifications: Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable