Skip to Content
Merck

50940

Guanidine hydrochloride

≥99.0% (AT)

Synonym(s):

Aminoformamidine hydrochloride, Aminomethanamidine hydrochloride, Guanidinium chloride

Slide 1 of 5
Sign In to View Organizational & Contract Pricing

Select a Size

100 G

CZK 2,390.00

500 G

CZK 11,100.00

1 KG

CZK 14,300.00

5 KG

CZK 68,100.00

CZK 2,390.00

Please contact Customer Service for Availability
Request a Bulk Order

About This Item

Linear Formula:
NH2C(=NH)NH2 · HCl
CAS Number:
50-01-1
Molecular Weight:
95.53
Beilstein:
3591990
EC Number:
200-002-3
MDL number:
MFCD00013026
UNSPSC Code:
12352107
PubChem Substance ID:
329757653
NACRES:
NA.55

Key Documents

View All Documentation

Skip To

Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Assay

≥99.0% (AT)

form

solid

ign. residue

≤0.1% (as SO4)

pH

(25 °C, 4.6 - 6/573 g/L)

mp

180-185 °C (lit.)

solubility

H2O: 6 M at 20 °C, clear, colorless

density

1.3 g/cm3 (lit.)

anion traces

sulfate (SO42-): ≤50 mg/kg

cation traces

Ca: ≤20 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg

SMILES string

Cl[H].NC(N)=N

InChI

1S/CH5N3.ClH/c2-1(3)4;/h(H5,2,3,4);1H

InChI key

PJJJBBJSCAKJQF-UHFFFAOYSA-N

Gene Information

human ... KCNA1(3736), KCNA10(3744), KCNA2(3737), KCNA3(3738), KCNA4(3739), KCNA5(3741), KCNA6(3742), KCNA7(3743), KCNB1(3745), KCNB2(9312), KCNC1(3746), KCNC2(3747), KCNC3(3748), KCNC4(3749), KCND1(3750), KCND2(3751), KCND3(3752), KCNF1(3754), KCNG1(3755), KCNG2(26251), KCNG3(170850), KCNG4(93107), KCNH1(3756), KCNH2(3757), KCNH3(23416), KCNH4(23415), KCNH5(27133), KCNH6(81033), KCNH7(90134), KCNH8(131096), KCNQ1(3784), KCNQ2(3785), KCNQ3(3786), KCNQ4(9132), KCNQ5(56479), KCNS1(3787), KCNS2(3788), KCNS3(3790), KCNV1(27012), KCNV2(169522)

Looking for similar products? Visit Product Comparison Guide

Related Categories

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
5095050933G4505
Guanidine hydrochloride ≥99.0% (AT)

Sigma-Aldrich

50940

Guanidine hydrochloride

Guanidine hydrochloride ≥98%

Sigma-Aldrich

50950

Guanidine hydrochloride

Guanidine hydrochloride BioUltra, Molecular Biology, ≥99.5% (AT)

Sigma-Aldrich

50933

Guanidine hydrochloride

Guanidine hydrochloride organic base and chaeotropic agent, ≥99% (titration)

Sigma-Aldrich

G4505

Guanidine hydrochloride

assay

≥99.0% (AT)

assay

≥98%

assay

≥99.5% (AT)

assay

≥99% (titration)

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

400

form

solid

form

powder or crystals

form

powder or crystals

form

crystalline powder

density

1.3 g/cm3 (lit.)

density

1.3 g/cm3 (lit.)

density

1.3 g/cm3 (lit.)

density

1.3 g/cm3 (lit.)

solubility

H2O: 6 M at 20 °C, clear, colorless

solubility

H2O: 6 M, clear (100 Hazen)

solubility

H2O: 6 M at 20 °C, clear, colorless

solubility

H2O: 6 M

pH

(25 °C, 4.6 - 6/573 g/L)

pH

(25 °C, 4.6 - 6/573 g/L)

pH

4.5-6.0 (25 °C, 6 M in H2O)

pH

(25 °C, 4.6 - 6 at 573 g/L)

Application

Strong chaotropic agent useful for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302 + H332,H315,H319

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
WXBF7019V
WXBF6155V
WXBF3022V
WXBF2692V
WXBD8477V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Manula S B Rathnayake et al.
Cartilage, 13(2_suppl), 476S-485S (2021-03-23)
To investigate GAG-ECM (glycosaminoglycan-extracellular matrix) interactions in different cartilage types. To achieve this, we first aimed to determine protocols for consistent calculation of GAG content between cartilage types. Auricular cartilage containing both collagen and elastin was used to determine the
Masaatsu Adachi et al.
The Journal of organic chemistry, 78(4), 1699-1705 (2013-01-18)
We describe an improved synthesis of (-)-5,11-dideoxytetrodotoxin from an enone, which was used for synthesis of tetrodotoxin and its analogues in this laboratory. One of the major modifications was to establish a two-step guanidinylation of trichloroacetamide of a highly functionalized
Allan Joaquim Lamontanara et al.
Nature communications, 5, 5470-5470 (2014-11-18)
The activity of protein kinases is regulated by multiple molecular mechanisms, and their disruption is a common driver of oncogenesis. A central and almost universal control element of protein kinase activity is the activation loop that utilizes both conformation and
Marek Pruszynski et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 55(4), 650-656 (2014-03-01)
Nanobodies are approximately 15-kDa proteins based on the smallest functional fragments of naturally occurring heavy chain-only antibodies and represent an attractive platform for the development of molecularly targeted agents for cancer diagnosis and therapy. Because the human epidermal growth factor
Stefan J Kempf et al.
PloS one, 9(10), e110464-e110464 (2014-10-21)
Patients suffering from brain malignancies are treated with high-dose ionising radiation. However, this may lead to severe learning and memory impairment. Preventive treatments to minimise these side effects have not been possible due to the lack of knowledge of the
View All Related Papers

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service