A0637
DL-2-Aminoadipic acid
≥99% (TLC), powder, gliotoxic
Synonym(s):
DL-α-Aminoadipic acid
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| Size/SKU | Availability | Price |
|---|---|---|
1 g | Please contact Customer Service for Availability | 2 610,00 CZK |
5 g | Please contact Customer Service for Availability | 8 760,00 CZK |
10 g | Please contact Customer Service for Availability | 15 000,00 CZK |
About This Item
Linear Formula:
HO2C(CH2)3CH(NH2)CO2H
CAS Number:
Molecular Weight:
161.16
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352106
EC Number:
208-809-2
MDL number:
Assay:
≥99%
Form:
powder
Product Name
DL-2-Aminoadipic acid, ≥99%
Quality Segment
assay
≥99%
form
powder
mp
196-198 °C (lit.)
storage temp.
2-8°C
SMILES string
NC(CCCC(O)=O)C(O)=O
InChI
1S/C6H11NO4/c7-4(6(10)11)2-1-3-5(8)9/h4H,1-3,7H2,(H,8,9)(H,10,11)
InChI key
OYIFNHCXNCRBQI-UHFFFAOYSA-N
Gene Information
rat ... Grin2b(24410)
Application
DL-2-Aminoadipic acid (AAA) has been used as an astrotoxin to kill astrocytes that prevent efficient integration of transplanted cells into the retina. It has also been used as a gliotoxin to study the effect of astrocytic swelling on the tortuosity.
Biochem/physiol Actions
DL-2-Aminoadipic acid (AAA) is a six-carbon homolog of glutamate and a gliotoxic compound. It is generally used to considerably reduce the number of astroglia in cerebellar cultures that acts as a model to study the mechanisms of a-aminoadipic acid induced glial toxicity.
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This Item | |||
|---|---|---|---|
| description ≥99% | description - | description solid | description 98% |
| assay ≥99% | assay - | assay - | assay 98% |
| form powder | form powder | form solid | form solid |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
| storage temp. 2-8°C | storage temp. - | storage temp. - | storage temp. - |
| mp 196-198 °C (lit.) | mp 227-229 °C (lit.) | mp - | mp 232 °C (dec.) (lit.) |
| Gene Information rat ... Grin2b(24410) | Gene Information human ... GRM1(2911), GRM2(2912), GRM3(2913), GRM4(2914), GRM5(2915), GRM6(2916), GRM7(2917), GRM8(2918) | Gene Information rat ... Grik1(29559), Grin2a(24409), Grin2b(24410) | Gene Information - |
Signal Word
Warning
Hazard Codes
Precautionary Statements
Hazard Classifications
Skin Sens. 1
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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