A1104

Anti-Angiopoietin-1 antibody produced in goat

affinity isolated antibody, lyophilized powder

• Synonym(s): Anti-ANG-1
• UNSPSC Code: 51111800
• NACRES: NA.41
• MDL number: MFCD06798694
• Conjugate: unconjugated
• Clone: polyclonal
• Application: ELISA (i), IHC, WB
• Citations: 7

Properties

• biological source: goat
• Quality Segment: 200
• recombinant: expressed in goat
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: lyophilized powder
• species reactivity: human
• technique(s): immunohistochemistry: 5-15 μg/mL using cells and tissues, indirect ELISA: 0.5-1.0 μg/mL, western blot: 0.1-0.2 μg/mL
• UniProt accession no.: Q15389
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... ANGPT1(284)

Description

General description

Angiopoietin 1 is an endothelial cell-specific protein that is a ligand for the TIE2 tyrosine receptor. Angiopoietin 1 is critical for mature blood vessel formation.

Angiopoietin-1 (ANG-1) activates Tie-2 signaling in endothelial cells to promote chemotaxis, cell survival, cell sprouting, vessel growth, and stabilization,. ANG-1 is closely related to ANG-2. Both ANG-1 and ANG-2, with their receptor Tie-2, regulate embryonic vasculogenesis and angiogenisis, adult angiogenic sprouting, as well as endothelial cell proliferation.

Immunogen

purified, NSO-derived, recombinant human ANG-1.

Application

Goat anti-angiopoietin-1 can be used for immunohistochemistry (5-15 μg/mL), indirect ELISA (0.5-1.0 μg/mL) and western blot (0.1-0.2 μg/mL).

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• PPE (personal protective equipment): Eyeshields, Gloves, type N95 (US)