Skip to Content
Merck

Key Documents

View All Documentation

Skip To

A3233

L-Arginase from bovine liver

Protein ≥70 % by biuret, powder

Synonym(s):

L-Arginine amidinase, L-Arginine amidino-hydrolase

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View
Size/SKUAvailabilityPrice
2500 units
Please contact Customer Service for Availability
18 300,00 CZK
12500 units
Please contact Customer Service for Availability
75 600,00 CZK
25000 units
Please contact Customer Service for Availability
131 700,00 CZK

About This Item

CAS Number:
9000-96-8
UNSPSC Code:
12352204
NACRES:
NA.77
EC Number:
232-570-3
MDL number:
MFCD00081368
EC Number:
3.5.3.1 (BRENDA, IUBMB)
Specific activity:
≥100 units/mg protein
Biological source:
bovine liver

18 300,00 CZK

Please contact Customer Service for Availability
​
Request a Custom Order
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

biological source

bovine liver

Quality Segment

form

powder

specific activity

≥100 units/mg protein

composition

Protein, ≥70% biuret

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

Gene Information

cow ... ARG2(518752)

General description

L-arginase is also called as L-arginine amidinohydrolase. It exists in two forms, such as arginase-1 and arginase-2. Arginase-1 is present in liver cells and arginase-2 is seen usually in extrahepatic tissues like, kidney, brain, skeletal muscle, small intestine and the lactating mammary gland. Arginase -2 is mapped to human chromosome 14q24.1−24.3.

Biochem/physiol Actions

L-arginase hydrolyze L-arginine into L-ornithine and urea, which is the last step of the urea cycle in the liver of ureotelic species. Arginase plays a major role in the mammalian immune system and the enzyme participates in several aspects of inflammation.
L-Arginase is the major degradative enzyme for arginine; converts arginine to ornithine.
L-Arginase is the major degradative enzyme for arginine; converts arginine to ornithine; deficiency is associated with spasticity and motor dysfunction.

Other Notes

One unit will cause the hydrolysis of 1.0 μmole of L-arginine per minute at pH 9.5 and 37 °C.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
13727911009A8094
L-Arginase from bovine liver Protein ≥70 % by biuret, powder

Sigma-Aldrich

A3233

L-Arginase from bovine liver

L-Arginine EMPROVE® EXPERT, EP, USP

SAFC

137279

L-Arginine

L-Arginine BioUltra, ≥99.5% (NT)

Sigma-Aldrich

11009

L-Arginine

L-Arginine from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 98.5-101.0%

Sigma-Aldrich

A8094

L-Arginine

description

Protein ≥70 % by biuret, powder

description

EMPROVE® EXPERT, EP, USP

description

BioUltra, ≥99.5% (NT)

description

from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 98.5-101.0%

Gene Information

cow ... ARG2(518752)

Gene Information

human ... NOS1(4842), NOS2(4843)
rat ... Ppm1a(24666)

Gene Information

human ... NOS1(4842), NOS2(4843)
rat ... Ppm1a(24666)

Gene Information

human ... NOS1(4842), NOS2(4843)
rat ... Ppm1a(24666)

biological source

bovine liver

biological source

non-animal source

biological source

-

biological source

non-animal source

specific activity

≥100 units/mg protein

specific activity

-

specific activity

-

specific activity

-

form

powder

form

crystalline powder

form

powder or crystals

form

powder

UniProt accession no.

Q58DL1

UniProt accession no.

-

UniProt accession no.

-

UniProt accession no.

-

storage temp.

−20°C

storage temp.

-

storage temp.

-

storage temp.

-

Pictograms

Health hazard
GHS08

Signal Word

Danger

Hazard Codes

H334

Precautionary Statements

P261 - P284 - P501

Hazard Classifications

Resp. Sens. 1

Storage Class

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Questions

  1. I want to use this enzyme at a neutal pH, could you please comment on the activity and how much reduction in enzyme activity and specificity would be happening due to the change in the pH?

    1 answer

    1. L-Arginase typically exhibits optimal activity at pH 9.5 and 37 °C. While the product is likely to retain some degree of potency, the enzymatic activity of this material at neutral pH has not been determined. The enzyme is known to be rapidly inactivated at pH values below 6, according to "The Reversible Inactivation of Rat-Liver Arginase at Low pH". Please see the link below, Figure 1, which shows the Inactivation of arginase at different pH values:
      https://febs.onlinelibrary.wiley.com/doi/pdf/10.1111/j.1432-1033.1972.tb01809.x

      Please see the link below to review an additional article highlighting the relationship between pH and mouse liver arginase.
      https://www.jstage.jst.go.jp/article/biochemistry1922/45/12/45_12_1011/_pdf

      Helpful?

Reviews

No rating value

Active Filters