A4044

2,3′-Anhydrothymidine

• Empirical Formula (Hill Notation): C₁₀H₁₂N₂O₄
• CAS Number: 15981-92-7
• Molecular Weight: 224.21
• MDL number: MFCD00233554
• UNSPSC Code: 41106305
• PubChem Substance ID: 329770848
• NACRES: NA.51
• eCl@ss: 32119108
• Assay: ≥97% (TLC)
• Form: powder
• Solubility: methanol: 50 mg/mL, clear, colorless to faintly yellow
• Storage temp.: −20°C

Properties

• assay: ≥97% (TLC)
• form: powder
• solubility: methanol: 50 mg/mL, clear, colorless to faintly yellow
• storage temp.: −20°C
• SMILES string: CC1=C[N@@H]2[C@H]3C[C@@H](OC2=NC1=O)[C@@H](CO)O3
• InChI: 1S/C10H12N2O4/c1-5-3-12-8-2-6(7(4-13)15-8)16-10(12)11-9(5)14/h3,6-8,13H,2,4H2,1H3/t6-,7-,8-/m1/s1
• InChI key: JCSNHEYOIASGKU-BWZBUEFSSA-N

Description

Application

2,3′-Anhydrothymidine may be derivitized to 5′-benzoyl-2′,3′-anhydrothymidine for use in the synthesis of 5′-Derivatives of 3′-(tetrazole-2′-yl)-3′-deoxythymidines. 2,3′-Anhydrothymidine may be contacted with thioacetic acid to produce 3′-S-acetyl-3′-thio-2′-deoxynucleosides.

Safety Information

• Storage Class: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• PPE (personal protective equipment): Eyeshields, Gloves, type N95 (US)