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B4558

BW B70C

>98% (HPLC), solid

Synonym(s):

N-[3-[3-4(-Fluorophenoxy)phenyl]-1-methyl-2-propenyl]-N-hydroxyurea

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Size/SKUAvailabilityPrice
10 mg
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5 270,00 CZK

About This Item

Empirical Formula (Hill Notation):
C17H17FN2O3
CAS Number:
Molecular Weight:
316.33
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
MDL number:
Assay:
>98% (HPLC)
Form:
solid

5 270,00 CZK


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Quality Segment

assay

>98% (HPLC)

form

solid

color

white

solubility

DMSO: soluble 22 mg/mL

storage temp.

2-8°C

SMILES string

CC(\C=C\c1cccc(Oc2ccc(F)cc2)c1)N(O)C(N)=O

InChI

1S/C17H17FN2O3/c1-12(20(22)17(19)21)5-6-13-3-2-4-16(11-13)23-15-9-7-14(18)8-10-15/h2-12,22H,1H3,(H2,19,21)/b6-5+

InChI key

UAIYNMRLUHHRMF-AATRIKPKSA-N

Gene Information

human ... ALOX5AP(241)

Application

BW B70C has been used as a 5-lipoxygenase inhibitor to study its effects on eryptosis in erythrocytes.

Biochem/physiol Actions

BW B70C exhibits anti-inflammatory and anti-tumorigenic activities. It exhibits therapeutic effects against hepatocellular carcinoma. BW B70C plays a role in allergen-induced bronchoconstriction by reducing the allergic airway closure and glycoconjugate secretion.
Selective 5-lipoxygenase inhibitor.

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EMU053041PHR2629SAB1300959
description

>98% (HPLC), solid

description

targeting mouse Alox5ap

description

Pharmaceutical Secondary Standard; Certified Reference Material

description

saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution

assay

>98% (HPLC)

assay

-

assay

-

assay

-

form

solid

form

lyophilized powder

form

solid

form

buffered aqueous solution

Quality Level

100

Quality Level

100

Quality Level

300

Quality Level

100

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

−20°C

solubility

DMSO: soluble 22 mg/mL

solubility

-

solubility

-

solubility

-

color

white

color

-

color

-

color

-


Storage Class

10 - Combustible liquids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)



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