C1608

Monoclonal Anti-Cellular Retinoic Acid Binding Protein 1 antibody produced in mouse

clone C-1, ascites fluid, buffered aqueous solution

• Synonym(s): Anti-CRABP 1
• UNSPSC Code: 12352203
• NACRES: NA.41
• MDL number: MFCD02262690
• Conjugate: unconjugated
• Clone: C-1, monoclonal
• Application: ELISA (i), WB
• Citations: 9

Properties

• biological source: mouse
• Quality Segment: 200
• conjugate: unconjugated
• antibody form: ascites fluid
• antibody product type: primary antibodies
• clone: C-1, monoclonal
• form: buffered aqueous solution
• mol wt: antigen 16 kDa
• species reactivity: feline, turtle, monkey, rabbit, bovine, human, rat, chicken
• should not react with: (chameleon), frog, goldfish
• technique(s): indirect ELISA: suitable, western blot: suitable
• UniProt accession no.: P29762
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... CRABP1(1381) ; rat ... Crabp1(25061)

Description

General description

Cellular retinoic acid-binding protein 1 is a protein encoded by the CRABP1 gene in humans. It encodes a specific binding protein for a vitamin A family member. It is also referred as RBP5, CRABP, CRABPI and CRABP-I.

Immunogen

performic acid oxidized CRABP 1, purified from bovine retina.

Application

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Monoclonal Anti-Cellular Retinoic Acid Binding Protein 1 antibody produced in mouse is suitable for the following applications:

• indirect ELISA
• western blotting at a dilution of 1:1000
• immunofluorescence at a working dilution of 1:250

Biochem/physiol Actions

Cellular retinoic acid-binding protein 1 (CRABP1) is a prognostic marker for adenocarcinoma and clear cell carcinoma that exhibits chemo-resistance. It is a is a modulator of retinoic acid and plays an important role in retinoic acid-mediated differentiation and proliferation processes. CRABP1 also functions as a tumor-suppressor in esophageal epithelium and its epigenetic silencing may play a pivotal role during esophageal carcinogenesis.

Physical form

Solution in phosphate buffered saline containing 0.05% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 10 - Combustible liquids
• WGK: nwg
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• PPE (personal protective equipment): Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)