C6500

Cysteamine hydrochloride

suitable for cell culture

• Synonym(s): Cysteamine hydrochloride, β-Mercapto­ethylamine hydrochloride, 2-Amino­ethane­thiol hydrochloride, 2-Mercapto­ethyl­amine hydrochloride, Decarboxy­cysteine hydrochloride, β-Mercapto­ethylamine hydrochloride, 2-Amino­ethane­thiol hydrochloride, 2-Mercapto­ethyl­amine hydrochloride, Decarboxy­cysteine hydrochloride, Thio­ethanol­amine hydrochloride
• Linear Formula: HSCH₂CH₂NH₂ · HCl
• CAS Number: 156-57-0
• Molecular Weight: 113.61
• UNSPSC Code: 12352202
• Beilstein/REAXYS Number: 3590083
• MDL number: MFCD00012904
• NACRES: NA.79
• Form: (Powder to crystal)

Properties

• form: (Powder to crystal)
• Quality Segment: 200
• technique(s): cell culture | mammalian: suitable
• mp: 67-71 °C
• solubility: soluble (50mg/ml)
• shipped in: wet ice
• storage temp.: 2-8°C
• SMILES string: Cl[H].NCCS
• InChI: 1S/C2H7NS.ClH/c3-1-2-4;/h4H,1-3H2;1H
• InChI key: OGMADIBCHLQMIP-UHFFFAOYSA-N

Description

General description

Cysteamine is a chemical compound that can be biosynthesized in mammals, including humans, by the degradation of coenzyme A. The intermediate pantetheine is broken down into cysteamine and pantothenic acid. It is the biosynthetic precursor to the neurotransmitter hypotaurine. It is a stable aminothiol, containing both an amine and a thiol functional groups. Cysteamine is a white, water-soluble solid. It is often used as salts of the ammonium derivative including the hydrochloride, phosphocysteamine, and the bitartrate.

Application

Cysteamine derived from cysteine degradation is the simplest stable aminothiol. Cysteamine is used in the biosynthesis of coenzyme A (CoA). Cysteamine may be useful in studies on oxidative stress and glycation (transglycating agent). Cysteamine is a substrate useful to study the specificity and kinetics of cysteamine (2-aminoethanethiol) dioxygenase(s) (ADO).

Features and Benefits

Cysteamine Hydrochloride or cysteamine is a mercaptoethylamine hydrochloride salt reductant that forms in mammals from pantetheine formation by degrading Coenzyme A. It has been used as a cystine depleting agent as well as a somatostatin inhibitor.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Codes: H302,H317,H319,H335
• Precautionary Statements: P261 - P264 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Sens. 1 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable