Please see the link below to for the product datasheet:
https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/218/613/c6645pis.pdf
C6645
Cytosine β-D-arabinofuranoside hydrochloride
≥99% (HPLC), synthetic (inorganic), crystalline
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Synonym(s):
Arabinosylcytosine hydrochloride, 1-(β-D-Arabinofuranosyl)cytosine hydrochloride, Ara-C hydrochloride, Arabinocytidine hydrochloride, Cytarabine hydrochloride, Cytosine arabinoside hydrochloride
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| Size/SKU | Availability | Price |
|---|---|---|
25 mg | Please contact Customer Service for Availability | 1 360,00 CZK |
100 mg | Please contact Customer Service for Availability | 1 910,00 CZK |
500 mg | Please contact Customer Service for Availability | 6 490,00 CZK |
1 g | Please contact Customer Service for Availability | 10 400,00 CZK |
5 g | Please contact Customer Service for Availability | 36 000,00 CZK |
About This Item
Empirical Formula (Hill Notation):
C9H13N3O5 · HCl
CAS Number:
Molecular Weight:
279.68
NACRES:
NA.77
PubChem Substance ID:
EC Number:
200-713-9
MDL number:
UNSPSC Code:
12352208
Assay:
≥99% (HPLC)
Biological source:
synthetic (inorganic)
Form:
crystalline
Solubility:
water: 50 mg/mL, clear, colorless
Storage temp.:
2-8°C
1 360,00 CZK
Please contact Customer Service for Availability
Product Name
Cytosine β-D-arabinofuranoside hydrochloride, crystalline
biological source
synthetic (inorganic)
Quality Segment
assay
≥99% (HPLC)
form
crystalline
mp
197-198 °C (lit.)
solubility
water: 50 mg/mL, clear, colorless
storage temp.
2-8°C
SMILES string
Cl[H].NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O
InChI
1S/C9H13N3O5.ClH/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8;/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16);1H/t4-,6-,7+,8-;/m1./s1
InChI key
KCURWTAZOZXKSJ-JBMRGDGGSA-N
Gene Information
Application
Biochem/physiol Actions
Ara-C is phosphorylated to Ara-CTP and is incorporatee into DNA. It inhibits DNA replication by forming cleavage complexes with topoisomerase I resulting in DNA fragmentation, and ultimately induces apoptosis via the PKC signaling pathway. Does not inhibit RNA synthesis. Anti-leukemia agent.
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This Item | |||
|---|---|---|---|
| description crystalline | description crystalline, ≥90% (HPLC) | description United States Pharmacopeia (USP) Reference Standard | description European Pharmacopoeia (EP) Reference Standard |
| biological source synthetic (inorganic) | biological source - | biological source - | biological source - |
| Quality Level 200 | Quality Level 200 | Quality Level - | Quality Level - |
| assay ≥99% (HPLC) | assay ≥90% (HPLC) | assay - | assay - |
| form crystalline | form crystalline | form - | form - |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility water: 50 mg/mL, clear, colorless | solubility - | solubility - | solubility - |
Signal Word
Warning
Hazard Codes
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Muta. 2 - Repr. 2 - Skin Sens. 1
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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Hi I need the insert of this product please. Can you send me please? the batch number is SLCD2059
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