C7249
CI-1033
≥98% (HPLC), ErbB tyrosine kinase inhibitor, solid
Synonym(s):
Canertinib dihydrochloride, N-[4-(3-Chloro-4-fluorophenylamino)-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]acrylamide dihydrochloride, N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[3-(4-morpholinyl)propoxy]-6-quinazolinyl]-2-propenamide dihydrochloride, PD183805
Select a Size
| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Please contact Customer Service for Availability | 2 170,00 CZK 1 844,50 CZK |
25 mg | Please contact Customer Service for Availability | 8 140,00 CZK 6 919,00 CZK |
About This Item
1 844,50 CZK
List Price2 170,00 CZKSave 15%Product Name
CI-1033, ≥98% (HPLC)
Quality Segment
assay
≥98% (HPLC)
form
solid
solubility
DMSO: >10 mg/mL, H2O: >10 mg/mL
storage temp.
−20°C
SMILES string
Cl.Cl.Fc1ccc(Nc2ncnc3cc(OCCCN4CCOCC4)c(NC(=O)C=C)cc23)cc1Cl
InChI
1S/C24H25ClFN5O3.2ClH/c1-2-23(32)30-21-13-17-20(14-22(21)34-9-3-6-31-7-10-33-11-8-31)27-15-28-24(17)29-16-4-5-19(26)18(25)12-16;;/h2,4-5,12-15H,1,3,6-11H2,(H,30,32)(H,27,28,29);2*1H
InChI key
JZZFDCXSFTVOJY-UHFFFAOYSA-N
Gene Information
human ... EGFR(1956), ERBB2(2064), ERBB4(2066)
Biochem/physiol Actions
Features and Benefits
1 of 1
This Item | |||
|---|---|---|---|
| description ≥98% (HPLC) | description A cell-permeable pyridinylfuranopyrimidine compound that acts as a potent and ATP-competitive inhibitor of DNA-PK, PI3-K, and mTOR. | description InSolution, ≥97%, potent ATP-competitive inhibitor of DNA-PK, PI3-K, and mTOR | description targeting human ERBB4 (2) |
| assay ≥98% (HPLC) | assay ≥97% (HPLC) | assay ≥97% (HPLC) | assay - |
| form solid | form solid | form liquid | form lyophilized powder |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level - |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| solubility DMSO: >10 mg/mL, H2O: >10 mg/mL | solubility DMSO: 5 mg/mL | solubility - | solubility - |
| Gene Information human ... EGFR(1956), ERBB2(2064), ERBB4(2066) | Gene Information - | Gene Information - | Gene Information human ... ERBB4(2066) |
Signal Word
Warning
Hazard Codes
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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