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C9033

β-Chloro-L-alanine hydrochloride

Alanine aminotransferase inhibitor

Synonym(s):

(R)-2-Amino-3-chloropropanoic acid, 3-Chloro-L-alanine

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Size/SKUAvailabilityPrice
250 mg
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7 770,00 CZK
5 g
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48 300,00 CZK

About This Item

Empirical Formula (Hill Notation):
C3H6ClNO2 · HCl
CAS Number:
Molecular Weight:
160.00
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352204
MDL number:

7 770,00 CZK


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biological source

synthetic

Quality Segment

assay

≥98% (TLC)

form

powder

mp

205 °C

solubility

water: 50 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

Cl[H].N[C@@H](CCl)C(O)=O

InChI

1S/C3H6ClNO2.ClH/c4-1-2(5)3(6)7;/h2H,1,5H2,(H,6,7);1H/t2-;/m0./s1

InChI key

IENJPSDBNBGIEL-DKWTVANSSA-N

Application

β-Chloro-L-alanine hydrochloride has been used:
  • as a substrate for screening tyrosine phenol lyase steady state kinetics
  • in the inhibition of serine palmitoyltransferase and cytotoxicity studies in lymphocyte Ly-1 cells
  • as an inhibitor of alanine transaminase in wheat germ cell-free protein synthesis system

Biochem/physiol Actions

β-Chloro-L-alanine hydrochloride is an inhibitor of alanine aminotransferase (ALAT). Inhibition of ALAT leads to suppression of tumor progression in lung carcinoma.

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This Item
C9650A2628CDS008779
description

Alanine aminotransferase inhibitor

description

≥95%

description

protease substrate

description

AldrichCPR

assay

≥98% (TLC)

assay

≥95%

assay

≥98% (TLC)

assay

-

biological source

synthetic

biological source

-

biological source

-

biological source

-

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

-

form

powder

form

powder

form

powder

form

solid

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

-

solubility

water: 50 mg/mL, clear, colorless

solubility

-

solubility

ethanol: 50 mg/mL, clear to slightly hazy

solubility

-


Pictograms

Exclamation mark

Signal Word

Warning

Hazard Codes

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

dust mask type N95 (US), Eyeshields, Gloves



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