D0195

Dimethylethylammoniumpropane sulfonate

≥97% (TLC)

• Synonym(s): NDSB 195
• Empirical Formula (Hill Notation): C₇H₁₇NO₃S
• CAS Number: 160255-06-1
• Molecular Weight: 195.28
• MDL number: MFCD01319124
• UNSPSC Code: 12161900
• NACRES: NA.25

Properties

• description: zwitterionic
• Quality Segment: 100
• assay: ≥97% (TLC)
• form: powder
• mol wt: 195.28 g/mol
• technique(s): LC/MS: suitable, protein quantification: suitable
• color: white
• application(s): detection
• storage temp.: room temp
• SMILES string: [S](=O)(=O)([O-])CCC[N+](CC)(C)C
• InChI key: NNCRHRDBFDCWPA-UHFFFAOYSA-N

Description

General description

Dimethylethylammoniumpropane sulfonate is a zwitterionic solubilizing agent with usefulness in protein crystallization.

Application

Dimethylethylammoniumpropane sulfonate has been used in a study to assess the functional properties of the separate subunits of the human DNA helicase II/Ku autoantigen. It has also been used in a study to investigate the swelling behaviors of copolymeric hydrogels in various saline solutions.

Non-detergent sulfobetaine is a compound used for non-denaturing protien purification. Increases the extraction yield of membrane, nuclear and cytoskeletal associated proteins. Zwitterionic over a wide pH range, easily removed by dialysis and no significant absorption in the near UV range. Specific applications include microsomal protein extraction, nuclear protein recovery, precipitation reduction in IEF, and membrane-bound protease purification.

Other Notes

This product is non-micelle forming.

Safety Information

• Storage Class: 11 - Combustible Solids
• WGK: WGK 3
• PPE (personal protective equipment): Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges