D4893

3,4-Dehydro-L-proline

≥98% (TLC), suitable for ligand binding assays

• Synonym(s): (S)-3-Pyrroline-2-carboxylic acid, 3,4-Didehydro-L-proline
• Empirical Formula (Hill Notation): C₅H₇NO₂
• CAS Number: 4043-88-3
• Molecular Weight: 113.11
• NACRES: NA.26
• PubChem Substance ID: 24893903
• eCl@ss: 32160406
• UNSPSC Code: 12352209
• EC Number: 223-738-7
• MDL number: MFCD00065964
• Beilstein/REAXYS Number: 5376764

Properties

• Product Name: 3,4-Dehydro-L-proline,
• assay: ≥98% (TLC)
• form: powder
• technique(s): ligand binding assay: suitable
• color: white
• mp: 248-250 °C
• application(s): peptide synthesis
• SMILES string: OC(=O)[C@H]1NCC=C1
• InChI: 1S/C5H7NO2/c7-5(8)4-2-1-3-6-4/h1-2,4,6H,3H2,(H,7,8)/t4-/m0/s1
• InChI key: OMGHIGVFLOPEHJ-BYPYZUCNSA-N

Description

General description

3,4-Dehydro-L-proline acts a prolyl-t-RNA synthetase.

Biochem/physiol Actions

3,4-Dehydro-L-proline is used as a substrate and inhibitor of various enzymes. 3,4-Dehydro-L-proline may be used to inhibit extensin biosynthesis. 3,4-Dehydro-L-proline is a alternate substrate of the amino acid oxidase, NikD. 3,4-Dehydro-L-proline inhibits collagen secretion by chondorcytes.

Safety Information

• Storage Class: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• PPE (personal protective equipment): Eyeshields, Gloves, type N95 (US)