D5318

DCP-LA

≥95% (HPLC), oil

• Synonym(s): 2-[(2-pentylcyclopropyl)methyl]cyclopropaneoctanoic acid, 8-[2-(2-pentyl-cyclopropylmethyl)-cyclopropyl]-octanoic acid, FR 236924
• Empirical Formula (Hill Notation): C₂₀H₃₆O₂
• CAS Number: 28399-31-7
• Molecular Weight: 308.50
• NACRES: NA.77
• PubChem Substance ID: 24724463
• UNSPSC Code: 12352200
• MDL number: MFCD09265251
• Assay: ≥95% (HPLC)
• Form: oil

Properties

• Quality Segment: 100
• assay: ≥95% (HPLC)
• form: oil
• color: clear
• solubility: DMSO: >2 mg/mL
• storage temp.: 2-8°C
• SMILES string: CCCCCC1CC1CC2CC2CCCCCCCC(O)=O
• InChI: 1S/C20H36O2/c1-2-3-7-10-16-13-18(16)15-19-14-17(19)11-8-5-4-6-9-12-20(21)22/h16-19H,2-15H2,1H3,(H,21,22)
• InChI key: CONYTTFKIUJZOF-UHFFFAOYSA-N

Description

Biochem/physiol Actions

DCP-LA is a selective PKC-epsilon (PKC-ε) activator.

DCP-LA is a selective PKC-epsilon (PKC-ε) activator. In the in situ PKC assay with a reversed phase high-performance liquid chromatography, DCP-LA significantly activated PKC in PC-12 cells in a concentration (10 nM-100 μM)-dependent manner, with the maximal effect at 100 nM. DCP-LA has over a 7-fold greater potency for activation of PKC-ε over other PKC isozymes.

Features and Benefits

This compound is featured on the PKC page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety Information

• Storage Class: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• PPE (personal protective equipment): Eyeshields, Gloves, type N95 (US)