D5946
PD 150606
≥97% (HPLC)
Synonym(s):
(2Z)-3-(4-iodophenyl)-2-mercapto-2-Propenoic acid, 3-(4-iodophenyl)-2-mercapto-(Z)-2-propenoic acid
Select a Size
| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Please contact Customer Service for Availability | 3 290,00 CZK |
25 mg | Please contact Customer Service for Availability | 13 100,00 CZK |
About This Item
Quality Segment
assay
≥97% (HPLC)
form
powder
storage condition
protect from light
color
yellowish
solubility
DMSO: >20 mg/mL
storage temp.
−20°C
SMILES string
OC(=O)\C(S)=C\c1ccc(I)cc1
InChI
1S/C9H7IO2S/c10-7-3-1-6(2-4-7)5-8(13)9(11)12/h1-5,13H,(H,11,12)/b8-5-
InChI key
DJCVSFWGKYHMKH-YVMONPNESA-N
Biochem/physiol Actions
1 of 1
This Item | |||
|---|---|---|---|
| description ≥97% (HPLC) | description A cell-permeable, non-competitive, selective non-peptide calpain inhibitor [Ki = 210 nM for calpain-1 and 370 nM for calpain-2. | description An extremely potent, cell-permeamble, reversible, ATP-competitive and specific inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR; IC50 = 25 pM; Ki = 6 pM). | description The non-permeant fluorogenic Calpain Substrate III is made cell-permeable by a c-terminal heptaarginine extension via a Glu linkage. |
| assay ≥97% (HPLC) | assay ≥95% (HPLC) | assay ≥97% (HPLC) | assay ≥95% (HPLC) |
| form powder | form solid | form solid | form lyophilized solid |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| solubility DMSO: >20 mg/mL | solubility DMSO: 100 mg/mL, methanol: 25 mg/mL | solubility DMSO: 5 mg/mL | solubility DMSO: 5 mg/mL |
| storage condition protect from light | storage condition OK to freeze, protect from light | storage condition OK to freeze, protect from light | storage condition OK to freeze, desiccated (hygroscopic), protect from light |
Signal Word
Danger
Hazard Codes
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Oral - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
Target Organs
Respiratory system
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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