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D7692

Diethylumbelliferyl phosphate

≥98% (HPLC), cholesterol esterase inhibitor, oil

Synonym(s):

DEUP, UBP

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Size/SKUAvailabilityPrice
5 mg
Please contact Customer Service for Availability
4 410,00 CZK
25 mg
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13 700,00 CZK
11 645,00 CZK

About This Item

Empirical Formula (Hill Notation):
C14H17O6P
CAS Number:
Molecular Weight:
312.25
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
oil

4 410,00 CZK


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Product Name

Diethylumbelliferyl phosphate, ≥98% (HPLC), oil

Quality Segment

assay

≥98% (HPLC)

form

oil

color

colorless to yellow

solubility

DMSO: >5 mg/mL

storage temp.

−20°C

SMILES string

CCOP(=O)(OCC)Oc1ccc2C(C)=CC(=O)Oc2c1

InChI

1S/C14H17O6P/c1-4-17-21(16,18-5-2)20-11-6-7-12-10(3)8-14(15)19-13(12)9-11/h6-9H,4-5H2,1-3H3

InChI key

GHGRYKAFUNNHBG-UHFFFAOYSA-N

Application

Diethylumbelliferyl phosphate has been used as a lipase inhibitor to treat wild-type myeloblasts for in vitro neutrophil differentiation assays.

Biochem/physiol Actions

Diethylumbelliferyl phosphate (DEUP), an organophosphate does not block protein kinase activity A in vitro.
Diethylumbelliferyl phosphate is a selective, potent cholesterol esterase inhibitor. It blocks steroidogenesis primarily by preventing cholesterol transport into the mitochondria of steroidogenic cells. Inhibitors of cholesterol esterase are anticipated to limit the absorption of dietary cholesterol. IC50 = 11.6 μM.

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This Item
1936275164M8883
description

≥98% (HPLC), oil

description

suitable for fluorescence, ≥95% (HPCE)

description

suitable for fluorescence, ≥95% (HPCE)

description

phosphatase substrate

assay

≥98% (HPLC)

assay

≥95% (HPCE)

assay

≥95% (HPCE)

assay

≥98% (HPLC)

form

oil

form

powder or crystals

form

solid

form

powder

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

200

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

solubility

DMSO: >5 mg/mL

solubility

DMSO: soluble, DMF: soluble

solubility

DMSO: soluble, chloroform: soluble, 2-methoxyethanol: soluble

solubility

water: 25 mg/mL, clear to very slightly hazy, colorless

color

colorless to yellow

color

-

color

-

color

-


Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Codes

Hazard Classifications

Acute Tox. 2 Oral

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges



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