Skip to Content
Merck

Key Documents

Skip To

D9150

2,3-Dimethoxy-5-methyl-p-benzoquinone

apoptosis inducer

Promotion Available

Synonym(s):

Coenzyme Q0

Sign In to View Organizational & Contract Pricing.

Spend 10 750 CZK — Save 5%; Spend 15 250 CZK — Save 10%; Spend 28 000 CZK — Save 15%*

Sign in to check eligibility. Shop Products

Select a Size

Change View
Size/SKUAvailabilityPrice
1 g
Please contact Customer Service for Availability
1 960,00 CZK
5 g
Please contact Customer Service for Availability
6 670,00 CZK

About This Item

Empirical Formula (Hill Notation):
C9H10O4
CAS Number:
Molecular Weight:
182.17
UNSPSC Code:
12352204
NACRES:
NA.51
PubChem Substance ID:
EC Number:
210-100-8
Beilstein/REAXYS Number:
1640422
MDL number:

1 960,00 CZK

Save Up To 15%


Please contact Customer Service for Availability

​
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist


Quality Segment

form

powder

mp

58-60 °C (lit.)

storage temp.

2-8°C

SMILES string

COC1=C(OC)C(=O)C(C)=CC1=O

InChI

1S/C9H10O4/c1-5-4-6(10)8(12-2)9(13-3)7(5)11/h4H,1-3H3

InChI key

UIXPTCZPFCVOQF-UHFFFAOYSA-N

General description

2,3-Dimethoxy-5-methyl-p-benzoquinone (Coenzyme Q0 or DMM) is present in all the cells including neural cells.

Application

2,3-Dimethoxy-5-methyl-p-benzoquinone has been used:
  • as a tau protein fibrillization inducer to determine the regions of tau involved in the formation of paired helical filaments (PHFs)
  • as a component in buffer B for cytochrome oxidation assay with subsaturating light
  • in the RPMI-1640 medium for 2,3-bis-(2-methoxy-4-nitro-5-sulphenyl)-(2H)-tetrazolium-5-carboxanilide (XTT) assay to quantify antifungal activity

Coenzyme Q0 inhibits (via radical quenching) reactions of gamma-irradiation induced homolytic cleavage of O-glycoside bonds in polysaccharides. Coenzyme Q0 induces apoptosis and modulates the cell cycle in estrogen receptor negative breast cancer cells. It is toxic to other cells such as insulin producing cells.

Biochem/physiol Actions

2,3-Dimethoxy-5-methyl-p-benzoquinone (Coenzyme Q0) interacts with tau protein and aids in the formation of filamentous structure.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
428566211311429074
description

apoptosis inducer

description

97%

description

98%

description

98%

form

powder

form

-

form

solid

form

solid

storage temp.

2-8°C

storage temp.

-

storage temp.

-

storage temp.

-

Quality Level

200

Quality Level

100

Quality Level

200

Quality Level

200

mp

58-60 °C (lit.)

mp

253-257 °C (dec.) (lit.)

mp

66-67 °C (lit.)

mp

54-58 °C (lit.)


Pictograms

Exclamation mark

Signal Word

Warning

Hazard Codes

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class

11 - Combustible Solids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

dust mask type N95 (US), Eyeshields, Gloves



Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library




Questions

Reviews

No rating value

Active Filters