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D9761

6-Deoxy-D-glucose

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Synonym(s):

D-Isorhamnose, Epifucose, Quinovose

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100 mg
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10 300,00 CZK
250 mg
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21 700,00 CZK

About This Item

Empirical Formula (Hill Notation):
C6H12O5
CAS Number:
7658-08-4
Molecular Weight:
164.16
UNSPSC Code:
12352200
NACRES:
NA.52
PubChem Substance ID:
24894327
EC Number:
231-622-2
Beilstein/REAXYS Number:
1723317
MDL number:
MFCD00061627

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Quality Segment

grade

Molecular Biology

assay

≥98% (TLC)

form

powder

storage temp.

−20°C

SMILES string

C[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C6H12O5/c1-2-3(7)4(8)5(9)6(10)11-2/h2-10H,1H3/t2-,3-,4+,5-,6?/m1/s1

InChI key

SHZGCJCMOBCMKK-GASJEMHNSA-N

General description

6-Deoxy-D-glucose is a structural homolog of D-glucose (dextrose) and stable analog. It lacks the hydroxyl group at carbon 6 position. It is also an analog of mannose.

Application

6-Deoxy-D-glucose has been used as a standard in the circular dichroism measurements. It has also been used as sugar to incubate starved Dictyostelium HMX44A.atg1-1 cells for microscopy studies.

Biochem/physiol Actions

2-Deoxy-D-glucose (2-DG) is used as a glycolytic inhibitor in studying the biological function of glucose. It is not metabolized, induces endoplasmic reticulum stress and hence, blocks the carbohydrate metabolism in cancer cells. It has therapeutic potential in targeting chemo-resistant hypoxic cancer cells. 2-DG halts the N-linked glycosylation by replacing mannose.

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This Item
72987G7000G6750
6-Deoxy-D-glucose

Sigma-Aldrich

D9761

6-Deoxy-D-glucose

2-Deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-D-glucose ≥97% (HPLC)

Sigma-Aldrich

72987

2-Deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-D-glucose

α-D-Glucose 1-phosphate disodium salt hydrate ≥97% (Enzymatic Purity, anhydrous)

Sigma-Aldrich

G7000

α-D-Glucose 1-phosphate disodium salt hydrate

α-D-Glucose 1-phosphate dipotassium salt hydrate ≥99% (HPLC), BioXtra

Sigma-Aldrich

G6750

α-D-Glucose 1-phosphate dipotassium salt hydrate

description

-

description

≥97% (HPLC)

description

≥97% (Enzymatic Purity, anhydrous)

description

≥99% (HPLC), BioXtra

assay

≥98% (TLC)

assay

≥97% (HPLC)

assay

≥97% (Enzymatic Purity, anhydrous)

assay

≥99% (HPLC)

grade

Molecular Biology

grade

-

grade

-

grade

-

Quality Level

200

Quality Level

100

Quality Level

200

Quality Level

200

form

powder

form

powder

form

powder

form

powder

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)

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    Certificates of Analysis (COA)

    Lot/Batch Number
    0000492556
    0000100943
    0000109342
    0000127392
    0000478300

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