In powder form, this material may be stored at ambient temperature. While long term stability studies at freezer temperatures have not been conducted, other commercially available products are listed as freezer storage items. Freezer storage is not expected to be detrimental to the compound, but may not extend the shelf life of the product. Allow the bottle to reach room temperature prior to opening in order to prevent moisture uptake. Stock solutions prepared in acetone, DMSO, alcohols, or dimethylformamide may be stored at -20°C when purged with inert gas.
E1631
β-Estradiol 17-valerate
≥98% (HPLC), powder
Synonym(s):
1,3,5(10)-Estratriene-3,17β-diol 17-pentanote
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| Size/SKU | Availability | Price |
|---|---|---|
1 g | Please contact Customer Service for Availability | 5 670,00 CZK |
About This Item
Empirical Formula (Hill Notation):
C23H32O3
CAS Number:
Molecular Weight:
356.50
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
213-559-2
MDL number:
Beilstein/REAXYS Number:
2480357
Assay:
≥98%
Form:
powder
Product Name
β-Estradiol 17-valerate, ≥98%
biological source
synthetic
Quality Segment
assay
≥98%
form
powder
technique(s)
ELISA: suitable
solubility
acetone: 25 mg/mL, hazy, colorless
shipped in
ambient
storage temp.
room temp
SMILES string
CCCCC(=O)OC1CCC2C3CCc4cc(O)ccc4C3CCC12C
InChI
1S/C23H32O3/c1-3-4-5-22(25)26-21-11-10-20-19-8-6-15-14-16(24)7-9-17(15)18(19)12-13-23(20,21)2/h7,9,14,18-21,24H,3-6,8,10-13H2,1-2H3
InChI key
RSEPBGGWRJCQGY-UHFFFAOYSA-N
Application
β-Estradiol 17-valerate has been used:
- in an in-vivo assay, to synchronize the estrus cycle in athymic nude mice, to study the effect of recombinant pigment epithelium-derived factor (rPEDF) on induced ectopic fibroid lesions
- to study the influence of ovarian hormones on type II cGMP-dependent protein kinase (Prkg2) expression in mice
- to induce growth of estrogen-dependent tumor cells in athymic nude mice to establish a breast cancer mouse model
Biochem/physiol Actions
Estradiol valerate is observed to be useful for treating menopausal climacteric symptoms. β-Estradiol 17-valerate is used as a source of 17β-estradiol (E2) in in vitro fertilization, hormone replacement therapy, contraceptive drugs, to study reproductive disorders in animal models. It serves as growth promoter in animal farming. β-Estradiol 17-valerate is also used to culture single-sex population among fish. Studies in rats show that β-Estradiol 17-valerate has negative effects on the estrus cycle pattern.
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This Item | |||
|---|---|---|---|
| description ≥98% | description certified reference material, pharmaceutical secondary standard | description European Pharmacopoeia (EP) Reference Standard | description European Pharmacopoeia (EP) Reference Standard |
| assay ≥98% | assay - | assay - | assay - |
| form powder | form solid | form - | form - |
| Quality Level 100 | Quality Level 300 | Quality Level - | Quality Level - |
| storage temp. room temp | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility acetone: 25 mg/mL, hazy, colorless | solubility - | solubility - | solubility - |
| shipped in ambient | shipped in - | shipped in - | shipped in - |
Signal Word
Warning
Hazard Codes
Precautionary Statements
Hazard Classifications
Aquatic Chronic 1 - Carc. 2 - Lact. - Repr. 2
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
PPE (personal protective equipment)
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
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Can I store this β-Estradiol 17-valerate (E1631) at -20 degree fridge for long time storage?
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