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Ethyl-3,4-dephostatin

Name: Ethyl-3,4-dephostatin
Brand: SIGMA

>99% (HPLC), solid

Synonym(s):

3,4-Dihydroxy-N-ethyl-N-nitrosoaniline

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About This Item

Empirical Formula (Hill Notation):

C₈H₁₀N₂O₃

CAS Number:

237756-11-5

Molecular Weight:

182.18

NACRES:

NA.77

PubChem Substance ID:

24894445

UNSPSC Code:

12352200

MDL number:

MFCD04040000

Assay:

>99% (HPLC)

Form:

solid

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Properties

assay

>99% (HPLC)

form

solid

color

brown

solubility

DMSO: soluble 22 mg/mL, H₂O: soluble 8 mg/mL

storage temp.

2-8°C

SMILES string

CCN(N=O)c1ccc(O)c(O)c1

InChI

1S/C8H10N2O3/c1-2-10(9-13)6-3-4-7(11)8(12)5-6/h3-5,11-12H,2H2,1H3

InChI key

ZTXUSFPBLYQDDN-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Stable analog of dephostatin. Selective inhibitor of protein tyrosine phosphatase 1B and SHPTP-1. Does not inhibit CD45-associated phosphatases.

Features and Benefits

This compound is featured on the Phosphoprotein Phosphatases (Tyrosine) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Disclaimer

Store under nitrogen

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This Item	M9440	R2033	D0444
Sigma-Aldrich E1904 Ethyl-3,4-dephostatin	Sigma-Aldrich M9440 Methyl-3,4-dephostatin	Sigma-Aldrich R2033 RK-682	Sigma-Aldrich D0444 DT-2 trifluoroacetate salt
description >99% (HPLC), solid	description >98% (HPLC), powder	description ≥98% (HPLC)	description ≥95% (HPLC), film
form solid	form powder	form powder	form film
assay >99% (HPLC)	assay >98% (HPLC)	assay ≥98% (HPLC)	assay ≥95% (HPLC)
storage temp. 2-8°C	storage temp. 2-8°C	storage temp. −20°C	storage temp. −20°C
solubility DMSO: soluble 22 mg/mL, H₂O: soluble 8 mg/mL	solubility H₂O: insoluble, DMSO: soluble 18 mg/mL	solubility DMSO, heptane and xylene: ≥8 mg/mL	solubility H₂O: 0.5 mg/mL, clear
color brown	color red-brown	color white to tan	color colorless to white

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)

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