F7553
FR 122047 hydrochloride
≥98% (HPLC), powder
Synonym(s):
1-[(4,5-Bis(4-methoxyphenyl)-2-thiazoyl)carbonyl]-4-methylpiperazine hydrochloride
Select a Size
| Size/SKU | Availability | Price |
|---|---|---|
25 mg | Please contact Customer Service for Availability | 17 400,00 CZK |
About This Item
17 400,00 CZK
biological source
synthetic (organic)
Quality Segment
assay
≥98% (HPLC)
form
powder
color
faintly yellow
solubility
methylene chloride: 50 mg/mL, slightly hazy, yellow
shipped in
wet ice
storage temp.
2-8°C
SMILES string
Cl[H].COc1ccc(cc1)-c2nc(sc2-c3ccc(OC)cc3)C(=O)N4CCN(C)CC4
InChI
1S/C23H25N3O3S.ClH/c1-25-12-14-26(15-13-25)23(27)22-24-20(16-4-8-18(28-2)9-5-16)21(30-22)17-6-10-19(29-3)11-7-17;/h4-11H,12-15H2,1-3H3;1H
InChI key
YWMAVHIKOAOSFM-UHFFFAOYSA-N
Biochem/physiol Actions
1 of 1
This Item | |||
|---|---|---|---|
| description ≥98% (HPLC), powder | description The COX-1 Inhibitor, FR122047, also referenced under CAS 130717-51-0, controls the biological activity of COX-1. This small molecule/inhibitor is primarily used for Cell Signaling applications. | description A cell-permeable, non-steroidal anti-inflammatory drug (NSAID) of the oxicam family which preferentially inhibits the inducible isoform of COX-2 (IC50 = 4.7 µM) relative to COX-1 (IC50 = 36.6 µM). | description solid |
| biological source synthetic (organic) | biological source - | biological source - | biological source - |
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay - |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| form powder | form solid | form solid | form solid |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. - |
| solubility methylene chloride: 50 mg/mL, slightly hazy, yellow | solubility water: 4 mg/mL, DMSO: 5 mg/mL, 1 M HCl: 2 mg/mL | solubility DMSO: 10 mg/mL | solubility H2O: insoluble, DMSO: 2 mg/mL, ethanol: insoluble, 2-hydroxypropyl-β-cyclodextrin: insoluble |
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
PPE (personal protective equipment)
Eyeshields, Gloves, type N95 (US)
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.