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I6138

Idazoxan hydrochloride

α2-adrenoceptor antagonist

Synonym(s):

(±)-2-[1,4-Benzodioxan-2-yl]-2-imidazoline hydrochloride, RX 781094

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Size/SKUAvailabilityPrice
50 mg
Please contact Customer Service for Availability
2 840,00 CZK
2 414,00 CZK
100 mg
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3 760,00 CZK
3 196,00 CZK

About This Item

Empirical Formula (Hill Notation):
C11H12N2O2 · HCl
CAS Number:
Molecular Weight:
240.69
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:

2 414,00 CZK

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Product Name

Idazoxan hydrochloride,

Quality Segment

solubility

H2O: 50 mg/mL

SMILES string

Cl.C1CN=C(N1)C2COc3ccccc3O2

InChI

1S/C11H12N2O2.ClH/c1-2-4-9-8(3-1)14-7-10(15-9)11-12-5-6-13-11;/h1-4,10H,5-7H2,(H,12,13);1H

InChI key

MYUBYOVCLMEAOH-UHFFFAOYSA-N

Gene Information

Application

Idazoxan hydrochloride has been used to study the efficacy of antidepressant treatments that interact with multiple neurotransmitter systems.

Biochem/physiol Actions

α2-adrenoceptor antagonist; I2 imidazoline receptor agonist; I1 imidazoline receptor antagonist. Idazoxan can antagonize various behaviors generated by ethanol in a preclinical setting. It possesses neuroprotective activity against spinal cord injury, resulted due to experimental autoimmune encephalomyelitis (EAE) in mouse, an animal modal of multiple sclerosis (MS).

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This Item
CDS00365169870
description

-

description

AldrichCPR

description

suitable for microscopy, for the determination of Al, Be, Zn, Ga, In, Sc, 1-2 mol/mol water

Quality Level

100

Quality Level

-

Quality Level

200

solubility

H2O: 50 mg/mL

solubility

-

solubility

methanol: 0.5 g/10 mL, brown

Gene Information

human ... ADRA2A(150), ADRA2B(151), ADRA2C(152)

Gene Information

-

Gene Information

human ... CYP1A2(1544)


Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Codes

Precautionary Statements

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

dust mask type N95 (US), Eyeshields, Faceshields, Gloves



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