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M2199

PMEG hydrate

≥98% (HPLC)

Synonym(s):

9-[2-(Phosphonomethoxy)ethyl]guanine hydrate

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Size/SKUAvailabilityPrice
25 mg
Please contact Customer Service for Availability
10 700,00 CZK

About This Item

Empirical Formula (Hill Notation):
C8H12N5O5P · xH2O
CAS Number:
Molecular Weight:
289.19 (anhydrous basis)
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352202
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated

10 700,00 CZK


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Quality Segment

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to off-white

solubility

DMSO: ≥5 mg/mL

storage temp.

2-8°C

SMILES string

O.NC1=Nc2c(ncn2CCOCP(O)(O)=O)C(=O)N1

InChI

1S/C8H12N5O5P.H2O/c9-8-11-6-5(7(14)12-8)10-3-13(6)1-2-18-4-19(15,16)17;/h3H,1-2,4H2,(H2,15,16,17)(H3,9,11,12,14);1H2

InChI key

BDVQXHFCXJXVND-UHFFFAOYSA-N

Biochem/physiol Actions

The acyclic nucleotide 9-(2-phosphonylmethoxyethyl)guanine (PMEG) forms an active phosphorylated metabolite, PMEG diphosphate (PMEGpp), in cells and causes cytotoxicity in dividing cells due to potent inhibition of the nuclear DNA polymerases resulting in inhibition of DNA synthesis and/or DNA repair.

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This Item
D6196SML0040SML0178
description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥95% (HPLC)

description

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥95% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: ≥5 mg/mL

solubility

H2O: ≥10 mg/mL

solubility

DMSO: ≥5 mg/mL

solubility

H2O: ≥5 mg/mL

storage condition

desiccated

storage condition

-

storage condition

-

storage condition

desiccated


Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Codes

Hazard Classifications

Acute Tox. 2 Oral

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3



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