PLA0140

Rabbit anti-Phospho KAP-1 (S824) Antibody, Affinity Purified

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• Synonym(s): E3 SUMO-protein ligase TRIM28, KAP-1, KAP1, KRAB [Kruppel-associated box domain]-associated protein 1, KRAB-associated protein 1, KRAB-interacting protein 1, KRIP-1, PPP1R157, RING finger protein 96, RNF96, TF1B, TIF1-beta, TIF1B, Tripartite motif-containing protein 28, nuclear corepressor KAP-1, protein phosphatase 1, regulatory subunit 157, transcriptional intermediary factor 1-beta
• NACRES: NA.43
• UNSPSC Code: 12352203
• Species reactivity: mouse, human
• Technique(s): immunocytochemistry: 1:200-1:1,000, immunofluorescence: 1:200-1:1,000, immunohistochemistry: 1:2000-1:1,000, immunoprecipitation (IP): 2-10 μg/mg, western blot: 1:2,000-1:10,000
• Application: ICC, IF, IHC, IP, WB
• Citations: 4

Properties

• biological source: rabbit
• Quality Segment: 100
• antibody form: affinity purified immunoglobulin
• antibody product type: primary antibodies
• species reactivity: mouse, human
• technique(s): immunocytochemistry: 1:200-1:1,000, immunofluorescence: 1:200-1:1,000, immunohistochemistry: 1:2000-1:1,000, immunoprecipitation (IP): 2-10 μg/mg, western blot: 1:2,000-1:10,000
• accession no.: NP_005753.1
• shipped in: wet ice
• storage temp.: 2-8°C
• target post-translational modification: phosphorylation (pSer824)
• Gene Information: human ... KIFAP3(22920)

Description

Immunogen

Immunogen was a synthetic phosphorylated peptide, which represented a portion of human KRAB-Associated Protein 1 surrounding Serine 824 according to the numbering given in entry NP_005753.1 (GeneID 10155).

Physical form

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

Other Notes

KAP-1 (KRAB-Associated Protein 1) is a member of the tripartite motif RBCC/Trim domain family that contains a RING finger domain, B boxes, and an alpha helical coiled coil region. KAP-1 functions as a corepressor by interacting with the KRAB domain of KRAB zinc-finger transcriptional repressors. KAP-1 also appears to function as a scaffold for chromatin-remodeling complexes involved in transcriptional repression.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable