RAB0780

Mouse Tyro3 / Tyrosine-protein Kinase Receptor TYRO3 ELISA Kit

• NACRES: NA.32
• UNSPSC Code: 41116158
• Gene information: mouse ... Tyro3(22174)
• Input: sample type cell culture supernatant(s); sample type serum; sample type plasma
• Species reactivity: mouse
• Storage temp.: −20°C
• Shipped in: wet ice

Properties

• species reactivity: mouse
• packaging: kit of 96 wells (12 strips x 8 wells)
• technique(s): ELISA: suitable
• input: sample type cell culture supernatant(s); sample type serum; sample type plasma
• assay range: inter-assay cv: <12%; intra-assay cv: <10%; sensitivity: 0.4 ng/mL; standard curve range: 0.416-100 ng/mL
• detection method: colorimetric
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: mouse ... Tyro3(22174)

Description

General description

The antibody pair provided in this kit recognizes mouse Tyro3.

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

Tyrosine-protein kinase receptor (TYRO3) is a transmembrane tyrosine kinase receptor. It plays a significant role in the brain development during embryogenesis. It plays an important role in apoptotic cell clearance. In hepatocellular carcinoma, it is associated with tumor growth, aggressiveness and liver dysfunction. Mutations in the TYRO3 gene intronic regions are linked with asthma. TYRO3 is also a suppressor of type 2 immunity. As part of the TAM (TYRO3, AXL and MER receptors) family, it is activated by PROS1 (protein S) and GAS6 (growth arrest-specific gene 6). Changes in the expression of TYRO3 are linked with the proliferation and survival of cancer cells. Absence of TYRO3 in mice results in neurological disorders.

Kit Components Also Available Separately

• RABTMB3

  ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)

  SDS
• RABSTOP3

  ELISA Stop Solution (Item I)

  SDS
• RABWASH4

  20X Wash Buffer (Item B)

  SDS

Safety Information

• Pictograms: GHS05
• Signal Word: Warning
• Hazard Codes: H290
• Precautionary Statements: P234 - P390
• Hazard Classifications: Met. Corr. 1
• Storage Class: 10 - Combustible liquids
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable