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S006

Ketanserin (+)-tartrate salt

≥97%, 5-HT2 serotonin receptor antagonist, solid

Synonym(s):

3-(2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl)-2,4(1H,3H)-quinazolinedione (+)-tartrate salt, R 41468 (+)-tartrate salt

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Size/SKUAvailabilityPrice
10 mg
Please contact Customer Service for Availability
2 190,00 CZK
50 mg
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7 390,00 CZK
250 mg
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25 300,00 CZK
500 mg
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42 000,00 CZK

About This Item

Empirical Formula (Hill Notation):
C22H22FN3O3 · C4H6O6
CAS Number:
Molecular Weight:
545.51
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352202
EC Number:
281-062-8
MDL number:
Assay:
≥97%
Form:
solid

2 190,00 CZK


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Product Name

Ketanserin (+)-tartrate salt, ≥97%, solid

Quality Segment

assay

≥97%

form

solid

color

white

solubility

ethanol: 3 mg/mL, DMSO: 52 mg/mL (lit.)(lit.), 0.1 M HCl: 6 mg/mL (lit.)(lit.)

storage temp.

2-8°C

SMILES string

O[C@H]([C@@H](O)C(O)=O)C(O)=O.Fc1ccc(cc1)C(=O)C2CCN(CC2)CCN3C(=O)Nc4ccccc4C3=O

InChI

1S/C22H22FN3O3.C4H6O6/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29;5-1(3(7)8)2(6)4(9)10/h1-8,16H,9-14H2,(H,24,29);1-2,5-6H,(H,7,8)(H,9,10)/t;1-,2-/m.1/s1

InChI key

KMTLTEVOQLMYRS-LREBCSMRSA-N

Gene Information

Application

Ketanserin (+)-tartrate salt has been used:
  • as a 5HT2A antagonist in Krebs-Henseleit buffer solution
  • for hormonal treatment to study the effects of exogenous manipulation of different hormonal systems in interaction with parasite infection on client′s behavior
  • to study the behavioural changes of incision pain rats

Biochem/physiol Actions

Selective 5-HT2 serotonin receptor antagonist.
Selective 5-HT2 serotonin receptor antagonist. Ketanserin significantly reduces nicotine self-administration in rats, supporting an unexpected involvement of serotonin in nicotine addiction.
Ketanserin stimulates collagen synthesis and is involved in wound healing.

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This Item
M5391M477339000
description

≥97%, solid

description

≥98% (titration), powder

description

-

description

≥99.0%

form

solid

form

powder

form

-

form

-

assay

≥97%

assay

≥98% (titration)

assay

-

assay

≥99.0%

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

100

storage temp.

2-8°C

storage temp.

-

storage temp.

-

storage temp.

-

solubility

DMSO: 52 mg/mL (lit.)(lit.), ethanol: 3 mg/mL, 0.1 M HCl: 6 mg/mL (lit.)(lit.)

solubility

H2O: 50 mg/mL

solubility

-

solubility

-

color

white

color

white to off-white

color

-

color

-


Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Codes

Precautionary Statements

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges



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