SML0910
TC3.6
≥98% (HPLC)
Synonym(s):
3-Phenyl-2,4(1H,3H)-quinazolinedithione
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| Size/SKU | Availability | Price |
|---|---|---|
25 mg | Please contact Customer Service for Availability | 8 520,00 CZK |
About This Item
Empirical Formula (Hill Notation):
C14H10N2S2
CAS Number:
Molecular Weight:
270.37
UNSPSC Code:
41106305
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
light orange to dark orange
solubility
DMSO: 20 mg/mL, clear
storage temp.
2-8°C
SMILES string
Sc1[n]([c](c3c(n1)cccc3)=S)c2ccccc2
InChI key
DJJOAJCVIYRELX-UHFFFAOYSA-N
Biochem/physiol Actions
TC3.6 is a PDE7 selective inhibitor (IC50 = 1.04 μM). In an Experimental Autoimmune Encephalomyelitis (EAE) murine model, TC3.6 reduced levels of IL-17, blocked infiltration of immune cells into the CNS and elevated levels of the Treg marker Foxp3. TC3.6 also enhances survival and differentiation of oligodendrocyte precursor cells.
TC3.6 is a PDE7 selective inhibitor.
Features and Benefits
This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
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This Item | |||
|---|---|---|---|
| description ≥98% (HPLC) | description ≥98% (HPLC) | description powder | description ≥98% (HPLC) |
| form powder | form powder | form powder | form powder |
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay - | assay ≥98% (HPLC) |
| Quality Level 100 | Quality Level 100 | Quality Level 200 | Quality Level 100 |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. - | storage temp. room temp |
| solubility DMSO: 20 mg/mL, clear | solubility DMSO: 15 mg/mL, clear | solubility H2O: insoluble, DMSO: 10 mg/mL | solubility H2O: 20 mg/mL, clear |
| color light orange to dark orange | color white to beige | color white to yellow | color white to beige |
Hazard Codes
Precautionary Statements
Hazard Classifications
Aquatic Chronic 4
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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