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SML2256

D3-βArr

≥98% (HPLC)

Synonym(s):

N-(1-Phenylethyl)-2-(1-piperazinyl)-4-quinazolinamine, N-(1-Phenylethyl)-2-(piperazin-1-yl)quinazolin-4-amine

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Size/SKUAvailabilityPrice
25 mg
Please contact Customer Service for Availability
7 350,00 CZK
6 247,50 CZK

About This Item

Empirical Formula (Hill Notation):
C20H23N5
CAS Number:
Molecular Weight:
333.43
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder

6 247,50 CZK

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assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

CC(C1=CC=CC=C1)NC2=NC(N3CCNCC3)=NC4=CC=CC=C42

InChI

1S/C20H23N5/c1-15(16-7-3-2-4-8-16)22-19-17-9-5-6-10-18(17)23-20(24-19)25-13-11-21-12-14-25/h2-10,15,21H,11-14H2,1H3,(H,22,23,24)

InChI key

LOGWGZNWEWFTJV-UHFFFAOYSA-N

Biochem/physiol Actions

D3-βArr is a positive allosteric modulator of TSHR (thyrotropin receptor) for β-Arr 1-mediated signaling that initiates translocation of β-Arr 1 by direct TSHR activation, while showing no agonistic effect on cAMP production. D3-βarr is a positive allosteric modulator for TSH-enhanced osteoblast differentiation.
positive allosteric modulator of TSHR (thyrotropin receptor) for β-Arr 1-mediated signaling

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This Item
182200539149
description

≥98% (HPLC)

description

The βARK1 Inhibitor, also referenced under CAS 24269-96-3, controls the biological activity of βARK1. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

description

A fluorogenic substrate probe useful for assaying trypsin-like activity of proteasome.

assay

≥98% (HPLC)

assay

≥97% (HPLC)

assay

≥98% (HPLC)

form

powder

form

solid

form

solid

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

solubility

DMSO: 2 mg/mL, clear

solubility

methanol: soluble, DMSO: 5 mg/mL

solubility

80% acetic acid: 50 mg/mL, methanol: soluble, DMSO: 200 mg/mL

color

white to beige

color

yellow to orange

color

white to off-white


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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