UC180

(S)-(+)-Nirvanol

• Synonym(s): (S)-(+)-5-Ethyl-5-phenyl-2,4-imidazolidinedione, (S)-(+)-5-Ethyl-5-phenylhydantoin
• Empirical Formula (Hill Notation): C₁₁H₁₂N₂O₂
• CAS Number: 65567-34-2
• Molecular Weight: 204.23
• NACRES: NA.77
• PubChem Substance ID: 329827656
• UNSPSC Code: 12161501
• MDL number: MFCD00272652
• Form: solid

Properties

• form: solid
• Quality Segment: 200
• color: off-white
• solubility: DMF: soluble
• storage temp.: 2-8°C
• SMILES string: CC[C@]1(NC(=O)NC1=O)c2ccccc2
• InChI: 1S/C11H12N2O2/c1-2-11(8-6-4-3-5-7-8)9(14)12-10(15)13-11/h3-7H,2H2,1H3,(H2,12,13,14,15)/t11-/m0/s1
• InChI key: UDTWZFJEMMUFLC-NSHDSACASA-N

Description

Biochem/physiol Actions

CYP2B6 metabolite of (R)-(-)-mephenytoin; anticonvulsant; hypnotic.

5-ethyl-5-phenylhydantoin (EPH) is a long-acting sedative. It is implicated to favor hepatocellular and thyroid follicular cell tumor progression.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Preparation Note

Nirvanol is soluble in DMF.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Codes: H302,H315,H319,H335
• Precautionary Statements: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• PPE (personal protective equipment): dust mask type N95 (US), Eyeshields, Gloves