sp3-sp3 Coupling reactions in the synthesis of natural products and biologically active molecules.

sp3-sp3 Coupling reactions in the synthesis of natural products and biologically active molecules.

Natural product reports (2014-02-28)

Egor Geist, Andreas Kirschning, Thomas Schmidt

ABSTRACT

This Highlight covers the current status of relatively unexplored sp(3)-sp(3) cross-coupling reactions with particular focus on natural product and related syntheses.

MATERIALS

Product Number

Brand

Product Description

268283

Sigma-Aldrich

Nickel, powder, <1 μm, 99.8% trace metals basis

267058

Sigma-Aldrich

Nickel, wire, diam. 0.5 mm, ≥99.99% trace metals basis

268259

Sigma-Aldrich

Nickel, foil, thickness 0.125 mm, ≥99.9%

357634

Sigma-Aldrich

Nickel, wire, diam. 0.25 mm, ≥99.9%

221678

Sigma-Aldrich

Raney^®-Nickel, W.R. Grace and Co. Raney^® 2800, slurry, in H₂O, active catalyst

203904

Sigma-Aldrich

Nickel, powder, <150 μm, 99.99% trace metals basis

510041

Sigma-Aldrich

Raney^®-Nickel, W.R. Grace and Co. Raney^® 4200, slurry, in H₂O, active catalyst

510033

Sigma-Aldrich

Raney^®-Nickel, W.R. Grace and Co. Raney^® 2400, slurry, in H₂O, active catalyst

510068

Sigma-Aldrich

Raney^®-Nickel, W.R. Grace and Co. Raney^® 3202, slurry, in H₂O, active catalyst

267007

Sigma-Aldrich

Nickel, foil, thickness 0.25 mm, 99.995% trace metals basis

GF61221989

Nickel, foil, 4mm disks, thickness 0.5mm, as rolled, 100%

GF63309494

Nickel, foil, 50mm disks, thickness 0.0125mm, 99.9%

GF00383981

Nickel, foil, 5m coil, thickness 0.125mm, annealed, 99.98%

GF01478189

Nickel, foil, 4mm disks, thickness 0.3mm, annealed, 99%

GF47998120

Nickel, foil, 4mm disks, thickness 0.125mm, annealed, 99.98%

GF67542194

Nickel, foil, 10mm disks, thickness 0.0025mm, 99.95%

GF41511293

Nickel, foil, 4mm disks, thickness 0.025mm, as rolled, 99.99+%

GF90338508

Nickel, foil, 4mm disks, thickness 0.03mm, 99.9%

GF44354932

Nickel, wire reel, 1m, diameter 1.0mm, as drawn, 99.99+%

GF74457399

Nickel, foil, 4mm disks, thickness 0.05mm, annealed, 99%

GF60742548

Nickel, foil, 2m coil, thickness 0.20mm, annealed, 99%

GF22538921

Nickel, foil, 0.5m coil, thickness 0.1mm, annealed, 99%

GF07190355

Nickel, foil, 4mm disks, thickness 0.0025mm, 99.95%

GF86231729

Nickel, foil, 4mm disks, thickness 0.05mm, as rolled, 99.99+%

GF27664836

Nickel, foil, 4mm disks, thickness 0.008mm, 99.95%

GF70648915

Nickel, foil, 2m coil, thickness 0.1mm, annealed, 99%

GF00494883

Nickel, foil, 10m coil, thickness 0.20mm, coil width 1mm, annealed, 99%

GF86630283

Nickel, foil, 0.5m coil, thickness 0.125mm, as rolled, 99.99+%

GF48190204

Nickel, foil, 4mm disks, thickness 0.0125mm, 99.9%

GF43777682

Nickel, foil, 10mm disks, thickness 0.0075mm, 99.95%