- Aluminum toxicity and astrocyte dysfunction: a metabolic link to neurological disorders.
Aluminum toxicity and astrocyte dysfunction: a metabolic link to neurological disorders.
Journal of inorganic biochemistry (2011-11-22)
Joseph Lemire, Vasu D Appanna
PMID22099161
ABSTRACT
Aluminum (Al) has been implicated in a variety of neurological diseases. However, the molecular mechanisms that enable Al to be involved in these disorders have yet to be fully delineated. Using astrocytes as a model of the cerebral cellular system, we have uncovered the biochemical networks that are affected by Al toxicity. In this review, we reveal how the inhibitory influence of Al on ATP production and on mitochondrial functions help generate globular astrocytes that are fat producing machines. These biological events may be the contributing factors to Al-triggered brain disorders.
MATERIALS
Product Number
Brand
Product Description
Aluminum, honeycomb, 300x300mm, thickness 10mm, cell size 6.3mm, cell wall 0.064mm, core density 0.083g/cm3, phenolic adhesive (resin), 99.5%
Aluminum, foam, 150x150mm, thickness 6.35mm, bulk density 0.2g/cm3, porosity 0.93, 8 pores/cm, aluminum 6101 grade, 98.5%
Aluminum, microleaf disks, 10mm, thinness 1.0μm, specific density 269.9μg/cm2, removable support, 99.999%
Aluminum, mesh, 900x900mm, nominal aperture 0.38mm, wire diameter 0.25mm, 40x40 wires/inch, open area 37%, plain weave mesh
Aluminum, rod, 200mm, diameter 12.0mm, as drawn, 99.999%
Aluminum, wire reel, 100m, diameter 0.25mm, as drawn, 99.5%
Aluminum, sphere, 100pcs, diameter 3.0mm, aluminum alloy 2017 precision sphere, grade 200, 95.2%
Aluminum, wire reel, 1000m, diameter 0.7mm, as drawn, 99.5%
Aluminum, rod, 500mm, diameter 15.0mm, as drawn, 99.999%
Aluminum, rod, 200mm, diameter 15.0mm, as drawn, 99.999%
Aluminum, wire reel, 100m, diameter 0.25mm, hard, 99.99+%
Aluminum, wire reel, 100m, diameter 0.5mm, as drawn, 99.95+%
Aluminum, wire reel, 0.5m, diameter 1.0mm, as drawn, 99.999%
Aluminum, wire reel, 100m, diameter 0.05mm, as drawn, 99.99+%
Aluminum, wire reel, 1000m, diameter 0.30mm, as drawn, 99.5%
Aluminum, wire reel, 100m, diameter 0.063mm, annealed, 99.99%
Aluminum, sphere, 200pcs, diameter 6.0mm, 99%
Aluminum, tube, 1000mm, outside diameter 0.55mm, inside diameter 0.4mm, wall thickness 0.075mm, as drawn, 99.5%
Aluminum, rod, 100mm, diameter 25.0mm, as drawn, 99.999%
Aluminum, sphere, 100pcs, diameter 1.0mm, aluminum alloy 2017 precision sphere, grade 200, 95.2%
Aluminum, tube, 0.1m coil, as drawn, outside diameter 0.30mm, inside diameter 0.2mm, wall thickness 0.05mm, 99.5%
Aluminum, mesh, 150x150mm, nominal aperture 0.38mm, wire diameter 0.25mm, 40x40 wires/inch, open area 37%, plain weave mesh
Aluminum, rod, 50mm, diameter 28mm, as drawn, 99.999%
Aluminum, rod, 100mm, diameter 6.0mm, as drawn, 99.999%
Aluminum, tube, 2m coil, as drawn, outside diameter 0.30mm, inside diameter 0.2mm, wall thickness 0.05mm, 99.5%
Aluminum, tube, 1000mm, outside diameter 0.86mm, inside diameter 0.76mm, wall thickness 0.05mm, as drawn, 99.5%
Aluminum, sphere, 100pcs, diameter 2.5mm, aluminum alloy 2017 precision sphere, grade 200, 95.2%
Aluminum, rod, 44mm, diameter 77.5mm, as drawn, 99.999%
Aluminum, rod, 500mm, diameter 5.0mm, as drawn, 99.999%
Aluminum, microleaf disks, 25mm, thinness 1.0μm, specific density 269.9μg/cm2, removable support, 99.999%