Understanding trans platinum complexes as potential antitumor drugs beyond targeting DNA.

Understanding trans platinum complexes as potential antitumor drugs beyond targeting DNA.

Journal of inorganic biochemistry (2012-07-24)

A G Quiroga

PMID22819649

ABSTRACT

This focused review is devoted to our advances in developing trans platinum complexes as antitumoral complexes, in particular those bearing aliphatic amines. It includes some fundamental aspects of the understanding of non conventional metallodrug mechanism. The perspective is arranged by those fundamental aspects and within each section only the most successful examples have been included and also those in which clearly SAR's (structure activity relationships) have been observed.

MATERIALS

Product Number

Brand

Product Description

GF37358051

Platinum, wire reel, 2m, diameter 0.25mm, annealed, may be used as one component of a thermocouple, 99.99%

GF10777721

Platinum, insulated wire, 0.5m, conductor diameter 0.125mm, insulation thickness 0.016mm, PTFE (polytetrafluoroethylene) insulation, 99.99%

GF02026965

Platinum, wire reel, 0.1m, diameter 0.005mm, wollaston, 99.9%

GF59659543

Platinum, insulated wire, 1m, conductor diameter 0.125mm, insulation thickness 0.014mm, polyester insulation, 99.99%

GF85399172

Platinum, tube, 100mm, outside diameter 1.2mm, inside diameter 1.0mm, wall thickness 0.1mm, as drawn, 99.95%

GF02883157

Platinum, wire reel, 0.2m, diameter 0.8mm, annealed, may be used as one component of a thermocouple, 99.99%

GF61330452

Platinum, wire reel, 2m, diameter 0.20mm, annealed, may be used as one component of a thermocouple, 99.99%

GF47005275

Platinum, rod, 6.5mm, diameter 6.0mm, 99.99+%

GF14510359

Platinum, foil, light tested, 25x25mm, thickness 0.05mm, as rolled, 99.95%

GF84918044

Platinum, insulated wire, 0.5m, conductor diameter 0.018mm, insulation thickness 0.002mm, polyester insulation, 99.99%

GF16142396

Platinum, wire reel, 10m, diameter 0.02mm, as drawn, 99.9%

GF16249327

Platinum, wire reel, 0.1m, diameter 0.40mm, as drawn, 99.99%

GF82054492

Platinum, foil, 0.1m coil, thickness 0.025mm, coil width 5mm, as rolled, 99.95%

GF96725054

Platinum, wire reel, 0.1m, diameter 0.001mm, wollaston, 99.9%

GF29464667

Platinum, microfoil, disks, 25mm, thinness 1.0μm, specific density 900μg/cm², permanent mylar 3.5μm support, 99.99+%

GF15051923

Platinum, foil, not light tested, 100x100mm, thickness 0.0075mm, as rolled, 99.95%

685453

Sigma-Aldrich

Platinum, nanopowder, <50 nm particle size (TEM)

GF71917005

Platinum, foil, 0.1m coil, thickness 0.025mm, coil width 8mm, as rolled, 99.95%

349372

Sigma-Aldrich

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357367

Sigma-Aldrich

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327492

Sigma-Aldrich

Platinum, wire, diam. 1.0 mm, 99.9% trace metals basis

349364

Sigma-Aldrich

Platinum, foil, thickness 0.025 mm, 99.99% trace metals basis

267171

Sigma-Aldrich

Platinum, wire, diam. 0.25 mm, 99.99% trace metals basis

349399

Sigma-Aldrich

Platinum, wire, diam. 1.5 mm, ≥99.9% trace metals basis

GF28802695

Platinum, foil, 25x25mm, thickness 0.25mm, as rolled, 99.999%

204013

Sigma-Aldrich

Platinum, powder, 99.995% trace metals basis

204048

Sigma-Aldrich

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373214

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298107

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Sigma-Aldrich

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