Thin layer chromatography (TLC) is a widely used separation technique for quantitative and qualitative analysis. It uses a thin layer of a stationary phase coated on a glass, plastic, or aluminum plate. A liquid solvent called the mobile phase carries the sample and separates it as it moves across the plate. It offers the advantages of simplicity, sensitivity, and rapid analysis over other separation techniques.
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Our classical thin layer chromatography plates are silica plates. They have a smooth and dense silica gel 60 coating to ensure narrow chromatographic bands. Classical plates are also available as aluminum TLC plates, glass TLC plates, or plastic TLC plates in a variety of plate dimensions, including our multiformat plates, and with two types of fluorescent indicators for UV detection. In addition to unmodified silica TLC plates, we also offer specialty TLC plates, including:
HPTLC plates provide decreased band diffusion and compact chromatographic zones or spots. HPTLC plates are available in various dimensions and backings, including our multiformat plates, and the option of two different fluorescent indicators. Our classic silica HPTLC plates enable fast and sensitive quantitative analysis of complex samples for both manual and instrumental use. We also offer a variety of specialty HPTLC plates, including:
Our MS-Grade plates enable direct mass spectrometric analysis of separated and dried samples on TLC and HPTLC plates. After chromatographic separation, our MS-Grade TLC plates can be used in either elution-based or desorption-based TLC-MS. MS-Grade plates are available either with or without fluorescent indicators and provide:
Preparative TLC plates are used for the analytical separation of large samples. Samples are typically loaded as a wide band rather than a spot and analyzed by UV-detection. Once resolved, sample bands are commonly recovered from the plate by scraping the adsorbent from the plate and eluting with a strong solvent
Our standardized TLC adsorbents are suitable for different TLC and PLC applications while providing reliable analytical results. We offer an extensive range of TLC adsorbents including:
Learn the advantage and strength of (HP)TLC- MS coupling technique along various Applications from different analytical fields using different MS techniques. Tips and tricks for the right handling are be presented, to avoid main basic defaults.