Skip to Content
Merck

328022

4-Methylhippuric acid

98%

Synonym(s):

N-(4-Methylbenzoyl)glycine, p-Toluric acid

Slide 1 of 1
Sign In to View Organizational & Contract Pricing

Select a Size

Pricing and availability is not currently available.

About This Item

Linear Formula:
CH3C6H4CONHCH2CO2H
CAS Number:
27115-50-0
Molecular Weight:
193.20
EC Number:
248-231-8
MDL number:
MFCD00020449
UNSPSC Code:
12352100
PubChem Substance ID:
24859708
NACRES:
NA.22

Key Documents

View All Documentation

Skip To

Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Assay

98%

form

powder

mp

163-165 °C (lit.)

functional group

amide
carboxylic acid

SMILES string

Cc1ccc(cc1)C(=O)NCC(O)=O

InChI

1S/C10H11NO3/c1-7-2-4-8(5-3-7)10(14)11-6-9(12)13/h2-5H,6H2,1H3,(H,11,14)(H,12,13)

InChI key

NRSCPTLHWVWLLH-UHFFFAOYSA-N

Related Categories

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
328014328006428558
4-Methylhippuric acid 98%

Sigma-Aldrich

328022

4-Methylhippuric acid

3-Methylhippuric acid 98%

Sigma-Aldrich

328014

3-Methylhippuric acid

2-Methylhippuric acid 98%

Sigma-Aldrich

328006

2-Methylhippuric acid

5-(4-Nitrophenyl)-2-furoic acid 96%

Sigma-Aldrich

428558

5-(4-Nitrophenyl)-2-furoic acid

assay

98%

assay

98%

assay

98%

assay

96%

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

form

powder

form

-

form

powder

form

-

mp

163-165 °C (lit.)

mp

138-140 °C (lit.)

mp

161-164 °C (lit.)

mp

255-257 °C (dec.) (lit.)

functional group

amide

functional group

amide, carboxylic acid

functional group

amide, carboxylic acid

functional group

carboxylic acid, nitro

General description

4-Methylhippuric acid is the major metabolite of xylene and has been determined in urine by gas chromatography.[1]

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCL9899
BCCJ0996
BCCG6024
BCCD1125
BCCB0142

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

P T Mayer et al.
AAPS pharmSci, 2(2), E14-E14 (2001-12-14)
To explore the independence of functional group contributions to permeability of nonelectrolytes across egg lecithin bilayers, the transport rates were measured of a series of alpha-substituted p-methylhippuric acids (-H, -Cl, -OCH3, -CN, -OH, -COOH, and -CONH2) across egg lecithin lipid
Measurement of exposure to xylenes by separate determination of m- and p-methylhippuric acids in urine.
M Morin et al.
Journal of chromatography, 210(2), 346-349 (1981-06-05)
Peter T Mayer et al.
Journal of pharmaceutical sciences, 91(3), 640-646 (2002-03-29)
The barrier domain solubility-diffusion theory of lipid bilayer permeability relates the permeability coefficient (P(m)) to the solute's partition coefficient (PC(barrier/w)) and diffusion coefficient (D(barrier)) in the ordered chain region of the bilayer that serves as the barrier region for polar
G Bieniek et al.
British journal of industrial medicine, 38(3), 304-306 (1981-08-01)
The separation of hippuric and m-methylhippuric acid as toluene and m-xylene metabolites present in urine of people exposed simultaneously to toluene and xylene is described. Chloroform was used for hippuric and m-methylhippuric acid extraction. Satisfactory separation of these metabolites was
Simultaneous determination of hippuric acid and o-, m- and p-methylhippuric acids in urine by high-performance liquid chromatography.
T Sakai et al.
Journal of chromatography, 276(1), 182-188 (1983-08-12)
View All Related Papers

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service