12-243

S6 Kinase/Rsk2 Substrate Peptide 2

Name: S6 Kinase/Rsk2 Substrate Peptide 2
Brand: MM

S6 Kinase/Rsk2 Substrate Peptide 2 primarily used in Kinase Assays.

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About This Item

UNSPSC Code:

12352202

eCl@ss:

32160405

NACRES:

NA.41

Key Documents

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Quality Level

100

manufacturer/tradename

Upstate^®

technique(s)

activity assay: suitable (kinase)

NCBI accession no.

NM_004586.2

UniProt accession no.

P51812

shipped in

wet ice

Gene Information

human ... RPS6KA3(6197)

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This Item	12-420	12-330	20-122
Sigma-Aldrich 12-243 S6 Kinase/Rsk2 Substrate Peptide 2	Sigma-Aldrich 12-420 Long S6 Kinase Substrate Peptide	Sigma-Aldrich 12-330 Casein Kinase 2 Substrate Peptide	Sigma-Aldrich 20-122 S6 Kinase Substrate Cocktail
technique(s) activity assay: suitable (kinase)	technique(s) activity assay: suitable (kinase)	technique(s) activity assay: suitable (kinase)	technique(s) activity assay: suitable (kinase)
Quality Level 100	Quality Level 100	Quality Level 300	Quality Level 100
shipped in wet ice	shipped in wet ice	shipped in wet ice	shipped in wet ice
UniProt accession no. P51812	UniProt accession no. Q15418	UniProt accession no. P67870	UniProt accession no. O75582, O75676, P23443, P51812, Q15349, Q15418, Q96S38, Q9UBS0, Q9UK32
Gene Information human ... RPS6KA3(6197)	Gene Information human ... RPS6KA1(6195)	Gene Information human ... CSNK2B(1460)	Gene Information human ... RPS6KA1(6195)
manufacturer/tradename Upstate^®	manufacturer/tradename Upstate^®	manufacturer/tradename Upstate^®	manufacturer/tradename Upstate^®

Biochem/physiol Actions

Protein Target: Rsk2

Target Sub-Family: AGC

Physical form

Lyophilized powder

Preparation Note

Lyophilized: Stable for 2 years at -20°C

Analysis Note

Routinely evaluated as a substrate for p90 Rsk-2 and p70 S6 Kinase.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Phosphatidylinositol 3'-kinase and p70s6k are required for insulin but not bisperoxovanadium 1,10-phenanthroline (bpV(phen)) inhibition of insulin-like growth factor binding protein gene expression. Evidence for MEK-independent activation of mitogen-activated protein kinase by bpV(phen).

C J Band et al.

The Journal of biological chemistry, 272(1), 138-145 (1997-01-03)

The hormonal regulation of insulin-like growth factor binding protein (IGFBP)-1 and -4 mRNA was compared in serum-free primary rat hepatocyte cultures. The combination of dexamethasone and glucagon (Dex/Gluc) strongly increased IGFBP-1 and IGFBP-4 mRNA levels. Insulin suppressed Dex/Gluc-stimulated IGFBP-1 but

Oxidative stress impairs insulin but not platelet-derived growth factor signalling in 3T3-L1 adipocytes

Tirosh, A., et al

The Biochemical Journal, 355, 757-763 (2001)

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