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Merck

07579

Synperonic® F 108

surfactant, non-ionic

Synonym(s):

Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol), Poly(propylene glycol)-block-poly(ethylene glycol)-block-poly(propylene glycol)

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About This Item

CAS Number:
9003-11-6
UNSPSC Code:
12352112
PubChem Substance ID:
24846082
NACRES:
NA.22
MDL number:
MFCD00082049

Key Documents

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Product Name

Synperonic® F 108, surfactant, non-ionic

InChI

1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2

InChI key

RVGRUAULSDPKGF-UHFFFAOYSA-N

impurities

≤0.5% water

mp

56-61 °C

hydroxyl value

6‑9 mg KOH/g

application(s)

detection

Quality Level

100

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Show Differences

1 of 4

This Item
86216P2443713538
Synperonic® F 108 surfactant, non-ionic

Sigma-Aldrich

07579

Synperonic® F 108

Synperonic® PE P105 surfactant

Sigma-Aldrich

86216

Synperonic® PE P105

Pluronic® F-127 powder, BioReagent, suitable for cell culture

Sigma-Aldrich

P2443

Pluronic® F-127

Synperonic® PE/P84

Sigma-Aldrich

713538

Synperonic® PE/P84

application(s)

detection

application(s)

-

application(s)

-

application(s)

-

Quality Level

100

Quality Level

-

Quality Level

200

Quality Level

100

impurities

≤0.5% water

impurities

≤1.0% water

impurities

-

impurities

≤1.0% water

mp

56-61 °C

mp

40-50 °C

mp

-

mp

-

hydroxyl value

6‑9 mg KOH/g

hydroxyl value

15‑19 mg

hydroxyl value

-

hydroxyl value

-

Legal Information

Synperonic is a registered trademark of Croda International PLC

Application

Synperonic® F 108 may be used as an adjuvant for lentiviral (LV) transduction. It possesses higher (LV) transduction efficiency than polybrene.[1]

General description

Synperonic F-108 is a polyoxyethylene-polyoxypropylene block copolymer. It has two hydrophilic groups that are attached to a central hydrophobic group that self-assembles in an aqueous solution into clusters known as micelles. This water-soluble surfactant is used as effective emulsification and solubilizing agent in a wide range of applications.

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000468967
0000468967
0000424995
0000424995
BCCM0896

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Ines Höfig et al.
The journal of gene medicine, 14(8), 549-560 (2012-08-14)
Although lentiviral transduction methods are widely used, their broader application is dependent upon the optimization of lentiviral transduction efficiency for a broad range of cell types. In the present study, we focus on the evaluation of two chemical classes with
Bishnubrata Patra et al.
Scientific reports, 6, 21061-21061 (2016-02-16)
Three-dimensional (3D) tumor spheroid possesses great potential as an in vitro model to improve predictive capacity for pre-clinical drug testing. In this paper, we combine advantages of flow cytometry and microfluidics to perform drug testing and analysis on a large
Feby Wijaya Pratiwi et al.
Biomedicines, 9(1) (2020-12-31)
Mesoporous silica nanoparticles (MSNs) have emerged as a prominent nanomedicine platform, especially for tumor-related nanocarrier systems. However, there is increasing concern about the ability of nanoparticles (NPs) to penetrate solid tumors, resulting in compromised antitumor efficacy. Because the physicochemical properties
Tsz Chung Lai et al.
Colloids and surfaces. B, Biointerfaces, 99, 27-37 (2011-10-18)
Polyplex particles formed with plasmid DNA (pDNA) and Pluronic P85-block-poly{N-[N-(2-aminoethyl)-2-aminoethyl]aspartamide} (P85-b-P[Asp(DET)]) demonstrated highly effective transfection ability compared to PEG-based block cationomer, PEG-b-P[Asp(DET)]. Ternary polyplexes comprising PEG-b-P[Asp(DET)], poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide)-b-P[Asp(DET)] (P(EPE)-b-P[Asp(DET)]) used as an analog of P85-b-P[Asp(DET)], and pDNA were
Houjian Gong et al.
Langmuir : the ACS journal of surfaces and colloids, 28(38), 13590-13600 (2012-09-08)
The block polyethers PEO-PPO-ph-PPO-PEO (BPE) and PPO-PEO-ph-PEO-PPO (BEP) are synthesized by anionic polymerization using bisphenol A as initiator. Compared with Pluronic P123, the aggregation behaviors of BPE and BEP at an air/water interface are investigated by the surface tension and
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Questions

1–3 of 3 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  3. Is this in powder or liquid form?

    1 answer

    1. This product is in solid form. The appearance specification is crystals or flakes. The exact form will be indicated on the lot-specific Certificate of Analysis. Certificates are available in the Documentation section of the product page.

      Please see the link below to access a specific lot or a sample Certificate:
      https://www.sigmaaldrich.com/product/sial/07579#product-documentation

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