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Merck

46404

Mebendazole

VETRANAL®, analytical standard

Synonym(s):

5-Benzoyl-2-benzimidazolecarbamic acid methyl ester, Mebendazol, Methyl N-(5-benzoyl-1H-benzimidazol-2-yl)carbamate

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About This Item

Empirical Formula (Hill Notation):
C16H13N3O3
CAS Number:
31431-39-7
Molecular Weight:
295.29
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329757164
EC Number:
250-635-4
Beilstein/REAXYS Number:
759809
MDL number:
MFCD00057872

Key Documents

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Product Name

Mebendazole, VETRANAL®, analytical standard

InChI key

OPXLLQIJSORQAM-UHFFFAOYSA-N

InChI

1S/C16H13N3O3/c1-22-16(21)19-15-17-12-8-7-11(9-13(12)18-15)14(20)10-5-3-2-4-6-10/h2-9H,1H3,(H2,17,18,19,21)

SMILES string

COC(=O)Nc1nc2cc(ccc2[nH]1)C(=O)c3ccccc3

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

Quality Level

100

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1 of 4

This Item
PHR2448M0215000BP1008
Mebendazole VETRANAL®, analytical standard

Supelco

46404

Mebendazole

Mebendazole Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR2448

Mebendazole

Mebendazole European Pharmacopoeia (EP) Reference Standard

M0215000

Mebendazole

Mebendazole British Pharmacopoeia (BP) Reference Standard

BP1008

Mebendazole

application(s)

clinical testing

application(s)

pharmaceutical small molecule

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical
pharmaceutical small molecule

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

-

technique(s)

-

format

neat

format

-

format

neat

format

neat

Quality Level

100

Quality Level

300

Quality Level

-

Quality Level

-

grade

analytical standard

grade

certified reference material, pharmaceutical secondary standard

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

shelf life

limited shelf life, expiry date on the label

shelf life

-

shelf life

-

shelf life

limited shelf life, expiry date on the label

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCG4824
BCCD7494
BCBR9633V

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Sara Carlert et al.
Molecular pharmaceutics, 9(10), 2903-2911 (2012-09-08)
The purpose of this study was to investigate in vivo intestinal precipitation of a model drug mebendazole, a basic BCS class II drug, using dogs with intestinal stomas for administration or sampling. After oral administration of a solution with an
Peter Nygren et al.
Journal of cancer research and clinical oncology, 139(12), 2133-2140 (2013-10-19)
In the present study, we screened a compound library containing 1,600 clinically used compounds with the aim to identify compounds, which potentially could be repositioned for colon cancer therapy. Two established colon cancer cell lines were tested using the fluorometric
Sivanesan Dakshanamurthy et al.
Journal of medicinal chemistry, 55(15), 6832-6848 (2012-07-12)
The most effective way to move from target identification to the clinic is to identify already approved drugs with the potential for activating or inhibiting unintended targets (repurposing or repositioning). This is usually achieved by high throughput chemical screening, transcriptome
Monica Longo et al.
Reproductive toxicology (Elmsford, N.Y.), 36, 78-87 (2013-01-05)
Filarial diseases affect millions of people in poverty-stricken areas. In 2011, an investigation of the potential of flubendazole as a safe, highly efficacious, and field-usable macrofilaricidal drug was begun by Drug for Neglected Diseases initiative. As part of the preclinical
Mebendazole and related anthelmintics.
H Van den Bossche et al.
Advances in pharmacology and chemotherapy, 19, 67-128 (1982-01-01)
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