P5413

Poly(ethylene glycol)

Name: Poly(ethylene glycol)
Brand: SIAL

Molecular Biology, average mol wt 8,000

Synonym(s):

Poly (ethylene oxide), Polyethylene glycol, PEG

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About This Item

Linear Formula:

H(OCH₂CH₂)_nOH

CAS Number:

25322-68-3

MDL number:

MFCD00081839

UNSPSC Code:

12352104

PubChem Substance ID:

24898639

NACRES:

NA.31

Key Documents

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grade

Molecular Biology

Quality Level

300

form

powder

mol wt

average mol wt 8,000

greener alternative product characteristics

Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.

sustainability

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solubility

water: soluble (approximately 630 mg/ml, 20 °C)

density

1.0845 g/mL at 70 °C
1.0689 g/mL at 90 °C

foreign activity

DNase, RNase and NICKase, none detected

greener alternative category

Aligned

SMILES string

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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Related Categories

Biochemicals

Detergents - Anionic, Cationic, Zwitterionic, Anti-foaming

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Show Differences

1 of 4

This Item	P3265	81268	81260
Sigma-Aldrich P5413 Poly(ethylene glycol)	Sigma-Aldrich P3265 Poly(ethylene glycol)	Sigma-Aldrich 81268 Poly(ethylene glycol)	Sigma-Aldrich 81260 Poly(ethylene glycol)
form powder	form liquid	form powder	form flakes
Quality Level 300	Quality Level 200	Quality Level 200	Quality Level 300
mol wt average mol wt 8,000	mol wt average mol wt 400	mol wt M_r 7000-9000	mol wt M_n 5,000-7,000, average M_n 6,000
density 1.0845 g/mL at 70 °C, 1.0689 g/mL at 90 °C	density 1.1254 g/cm³ at 20 °C, 1.0930 g/cm³ at 60 °C	density 1.0845 g/mL at 70 °C, 1.0689 g/mL at 90 °C	density -
grade for molecular biology	grade -	grade for molecular biology	grade -
solubility water: soluble (approximately 630 mg/ml, 20 °C)	solubility water: 100 mg/mL	solubility H₂O: 50 mg/mL at 20 °C, clear, colorless	solubility -

General description

Polyethylene glycol (PEG) is a polymer of ethylene oxide and water, obtained upon condensation.[1] PEGs are susceptible to oxidative degradation in the presence of air. Minimizing the exposure of PEG to elevated temperatures and/or exposure to oxygen or addition of an antioxidant can limit the amount of degradation. PEGs do not hydrolyze or deteriorate upon storage. PEGs do not support the growth of molds.[2]

Polyethylene glycol (PEG) is used in detergents, emulsifying agents, soaps, metal costing process, pharmaceutical preparations and cosmetics.[1] PEG is commonly used as a lubricant. It′s application is also observed in chromatographic stationary phases.[2] PEG prevents crystal formation in emulsions.[3]

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. Polyethylene glycol (PEG) is an eco-friendly, biodegradable polymer widely used in pharmaceuticals and cosmetics. Its non-toxic nature and versatility make it a sustainable choice, derived from renewable resources, contributing to greener product formulations. Click here for more information.

Application

Poly(ethylene glycol) has been used:

in protoplast suspension[4]
to prevent phase separation in emulsion[3]
in phage tail-like particles precipitation[5]
for purifying and intensifying products of polymerase chain reaction[6]

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number

0000496051

0000486933

0000486932

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Associations between HLA class I alleles and escape mutations in the hepatitis B virus core gene in New Zealand-resident Tongans

Abbott William GH, et al.

Journal of Virology, 84(1), 621-629 (2010)

Retinol encapsulated into amorphous Ca2+ polyphosphate nanospheres acts synergistically in MC3T3-E1 cells

Muller Werner EG, et al.

European Journal of Pharmaceutics and Biopharmaceutics, 93, 214-223 (2015)

Genes for the biosynthesis of the fungal polyketides hypothemycin from Hypomyces subiculosus and radicicol from Pochonia chlamydosporia

Reeves CD

Applied and Environmental Microbiology, 74(16), 5121-5129 (2008)

Induction and Purification of C. difficile Phage Tail-Like Particles

Clostridium difficile, 167-175 (2016)

An icosahedral virus as a fluorescent calibration standard: a method for counting protein molecules in cells by fluorescence microscopy.

John M Murray

Journal of microscopy, 267(2), 193-213 (2017-03-23)

The ability to replace genes coding for cellular proteins with DNA that codes for fluorescent protein-tagged versions opens the way to counting the number of molecules of each protein component of macromolecular assemblies in vivo by measuring fluorescence microscopically. Converting

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Questions

1–2 of 2 Questions

Anonymous

5 months ago

How can I determine the shelf life / expiration / retest date of this product?

1 answer
1. Technical Support
  
  5 months ago
  
  If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
  For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
  For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
  For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf
  
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Anonymous

a year ago

How is shipping temperature determined? And how is it related to the product storage temperature?

1 answer
1. Technical Support
  
  a year ago
  
  Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
  
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